Human Somatostatin Receptor 4 (SSTR4) ELISA Kit | SSTR4 elisa kit

Human Somatostatin Receptor 4 (SSTR4) ELISA Kit

Cat. Num. AAA3803255

• Gene Names: SSTR4; SS4R; SS4-R; SS-4-R
• Reactivity: Human
• Synonyms: Somatostatin Receptor 4 (SSTR4); Human Somatostatin Receptor 4 (SSTR4) ELISA Kit; SSTR4 elisa kit

• Reactivity: Human
• Sequence Length: 388

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 62.5 pg/ml-1000 pg/ml
• Sensitivity: 1 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for SSTR4 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofSSTR4in the sample, This SSTR4ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusSSTR4concentration. The concentration ofSSTR4in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 149944554
• NCBI GeneID: 6754
• NCBI GenBank Nucleotide #: NP_001043.2
• UniProt Accession #: P31391
• NCBI Official Full Name: somatostatin receptor type 4
• NCBI Official Synonym Full Names: somatostatin receptor 4
• NCBI Official Symbol: SSTR4
• NCBI Official Synonym Symbols: SS4R; SS4-R; SS-4-R
• NCBI Protein Information: somatostatin receptor type 4
• UniProt Protein Name: Somatostatin receptor type 4
• Protein Family: Somatostatin receptor
• UniProt Gene Name: SSTR4
• UniProt Synonym Gene Names: SS-4-R; SS4-R; SS4R
• UniProt Entry Name: SSR4_HUMAN

NCBI Description

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. [provided by RefSeq, Jul 2008]

Uniprot Description

SSTR4: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: neuropeptide binding; somatostatin receptor activity

Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; cell migration; positive regulation of MAPKKK cascade; neuropeptide signaling pathway; forebrain development; arachidonic acid metabolic process; negative regulation of cAMP metabolic process