KRT84 blocking peptide
KRT84 Peptide - middle region
Target Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome
NCBI and Uniprot Product Information
Uniprot Description
K84: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: keratin filament
Molecular Function: structural constituent of cytoskeleton; structural constituent of epidermis
Biological Process: hair follicle development; regulation of keratinocyte differentiation