EME2 blocking peptide
EME2 Peptide - middle region
Target Description: EME2 forms a heterodimer with MUS81 that functions as an XPF-type flap/fork endonuclease in DNA repair .
NCBI and Uniprot Product Information
NCBI Description
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
Uniprot Description
EME2: Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures. Belongs to the EME1/MMS4 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Deoxyribonuclease; EC 3.1.22.-
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nuclear chromatin
Molecular Function: crossover junction endodeoxyribonuclease activity; DNA binding
Biological Process: double-strand break repair; intra-S DNA damage checkpoint; replication fork processing; resolution of meiotic recombination intermediates
Research Articles on EME2
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Product Notes
The EME2 eme2 (Catalog #AAA3235298) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The EME2 Peptide - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EME2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the EME2 eme2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: TTARPHLAVI GLDAYLWSRQ HVSRGTQQPE SPKVAGAEVA VSWPEVEEVR. It is sometimes possible for the material contained within the vial of "EME2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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