Vgll2 blocking peptide
Vgll2 Peptide - C-terminal region
Target Description: Vgll2 may act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the Vestigial-like (Vgl) gene family and is upregulated during muscle differentiation. The product of this gene interacts with and modifies the DNA-binding properties of the transcription factor, TEF-1, and is important for muscle tissue development. Reduced expression of this gene leads to a reduction in the terminal differentiation of muscle cells. Alternate splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]
Uniprot Description
Function: May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles. Ref.1
Subunit structure: Interacts with TEFs. Binds to TEAD1/TEF1. Ref.1
Subcellular location: Nucleus Ref.1.
Tissue specificity: Skeletal muscle specific. Ref.2
Developmental stage: Expressed in the somitic myotome from E8.75 mouse embryos onwards and later on in skeletal muscle but not in the heart. Additional expression domains during development are detected in the pharyngeal pouches and clefts starting at E8.0 as well as in the cranial pharynx and in Rathkes pouch. Ref.2
Sequence similarities: Belongs to the vestigial family.
Research Articles on Vgll2
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Product Notes
The Vgll2 vgll2 (Catalog #AAA3228786) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The Vgll2 Peptide - C-terminal region reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Vgll2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Vgll2 vgll2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SELPFATDPY SPATLHGHLH QGAADWHHAH PHHAHPHHPY ALGGALGAQA. It is sometimes possible for the material contained within the vial of "Vgll2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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