Rabbit FOXA2 Polyclonal Antibody | anti-FOXA2 antibody

FOXA2 antibody - middle region

Cat. Num. AAA3200660

• Gene Names: FOXA2; HNF3B; TCF3B
• Reactivity: Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
• Applications: Western Blot
• Purity: Affinity Purified
• Synonyms: FOXA2; Polyclonal Antibody; FOXA2 antibody - middle region; anti-FOXA2 antibody

• Host: Rabbit
• Reactivity: Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity Purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: ASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALS
• Sequence Length: 457

• Applicable Applications for anti-FOXA2 antibody: Western Blot (WB)
• Homology: Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 77%; Rat: 92%
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXA2
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Host: RabbitTarget Name: FOXA2Sample Type: Human 721_BAntibody Dilution: 1.0ug/mlFOXA2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells)

Western Blot (WB)

(Host: RabbitTarget Name: FOXA2Sample Type: Human Fetal BrainAntibody Dilution: 1.0ug/ml)

Western Blot (WB)

(Host: RabbitTarget Name: FOXA2Sample Type: Human HepG2Antibody Dilution: 1.0ug/mlFOXA2 is strongly supported by BioGPS gene expression data to be expressed in HepG2)

Western Blot (WB)

(Sample Type: Human lung tissue protein extractsPrimary Dilution: 1:1000Secondary (Anti-Rabbit HRP sc-2004) Dilution: 1:1000)

Western Blot (WB)

(WB Suggested Anti-FOXA2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate)

Related Product Information for anti-FOXA2 antibody

This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Product Categories/Family for anti-FOXA2 antibody

Polyclonal; Transcription Factor; Transcription Regulation; Transcription Regulation; Chromatin & Nuclear Signaling; Stem Cells; Epigenetics; Disease Related; DNA/RNA/Protein Interactions; Transcription Factors; Cell Differentiation

NCBI and Uniprot Product Information

• NCBI GI #: 194394143
• NCBI GeneID: 3170
• NCBI Accession #: NP_068556
• NCBI GenBank Nucleotide #: NM_021784
• UniProt Accession #: Q9Y261
• Molecular Weight: 48kDa
• NCBI Official Full Name: hepatocyte nuclear factor 3-beta isoform 1
• NCBI Official Synonym Full Names: forkhead box A2
• NCBI Official Symbol: FOXA2
• NCBI Official Synonym Symbols: HNF3B; TCF3B
• NCBI Protein Information: hepatocyte nuclear factor 3-beta
• UniProt Protein Name: Hepatocyte nuclear factor 3-beta
• Protein Family: Forkhead box protein
• UniProt Gene Name: FOXA2
• UniProt Synonym Gene Names: HNF3B; TCF3B; HNF-3-beta; HNF-3B; TCF-3B
• UniProt Entry Name: FOXA2_HUMAN

NCBI Description

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]