Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of GCP3 (D238) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.)
Rabbit GCP3 Polyclonal Antibody | anti-GCP3 antibody
GCP3 (D238) Polyclonal Antibody
Gene Names
TUBGCP3; 104p; ALP6; GCP3; Spc98; SPBC98; Spc98p; Grip104
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
GCP3; Polyclonal Antibody; GCP3 (D238) Polyclonal Antibody; Gamma-tubulin complex component 3; GCP-3; hGCP3; Gamma-ring complex protein 104 kDa; h104p; hGrip104; Spindle pole body protein Spc98 homolog; hSpc98; TUBGCP3; anti-GCP3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GCP3 (D238) polyclonal antibody detects endogenous levels of GCP3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
907
Applicable Applications for anti-GCP3 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 204-252 of Human GCP3.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of GCP3 (D238) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of GCP3 (D238) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.)
Related Product Information for anti-GCP3 antibody
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP3 (gamma-tubulin complex component 3), also known as TUBGCP3 or SPBC98, localizes to the centrosome and is an ubiquitously expressed 907 amino acid member of the gamma-Tubulin complex.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 104kDa
NCBI Official Full Name
gamma-tubulin complex component 3 isoform 1
NCBI Official Synonym Full Names
tubulin gamma complex associated protein 3
NCBI Official Symbol
TUBGCP3
NCBI Official Synonym Symbols
104p; ALP6; GCP3; Spc98; SPBC98; Spc98p; Grip104
NCBI Protein Information
gamma-tubulin complex component 3
UniProt Protein Name
Gamma-tubulin complex component 3
Protein Family
UniProt Gene Name
TUBGCP3
UniProt Synonym Gene Names
GCP3; GCP-3; hGCP3; h104p; hGrip104; hSpc98
UniProt Entry Name
GCP3_HUMAN
Uniprot Description
GCP3: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: centriole; centrosome; membrane; cytoplasm; polar microtubule; spindle; cytosol
Molecular Function: protein binding; gamma-tubulin binding; structural constituent of cytoskeleton; structural molecule activity
Biological Process: single fertilization; mitotic cell cycle; G2/M transition of mitotic cell cycle; microtubule nucleation
Research Articles on GCP3
Similar Products
Product Notes
The GCP3 tubgcp3 (Catalog #AAA3013717) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCP3 (D238) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GCP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GCP3 tubgcp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
