Western Blot (WB)
(Western Blot (WB) analysis of FCRL5 polyclonal antibody at 1:500 dilutionLine1:Jurkat whole cell lysateLine2:PC12 whole cell lysateLine3:sp20 whole cell lysate)
Rabbit FCRL5 Polyclonal Antibody | anti-FCRL5 antibody
FCRL5 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
FCRL5; Polyclonal Antibody; FCRL5 Polyclonal Antibody; Fc receptor-like protein 5; FcR-like protein 5; FcRL5; BXMAS1; Fc receptor homolog 5; FcRH5; Immune receptor translocation-associated protein 2; CD307e; FCRH5; IRTA2; anti-FCRL5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
FCRL5 polyclonal antibody detects endogenous levels of FCRL5 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
998
Applicable Applications for anti-FCRL5 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human FCRL5.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of FCRL5 polyclonal antibody at 1:500 dilutionLine1:Jurkat whole cell lysateLine2:PC12 whole cell lysateLine3:sp20 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of FCRL5 polyclonal antibody at 1:500 dilutionLine1:Jurkat whole cell lysateLine2:PC12 whole cell lysateLine3:sp20 whole cell lysate)
Related Product Information for anti-FCRL5 antibody
The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 106kDa
NCBI Official Full Name
Fc receptor-like protein 5 isoform 2
UniProt Protein Name
Fc receptor-like protein 5
Protein Family
UniProt Gene Name
FCRL5
UniProt Synonym Gene Names
FCRH5; IRTA2; FcR-like protein 5; FcRL5; FcRH5
UniProt Entry Name
FCRL5_HUMAN
Uniprot Description
FCRL5: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32). 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell surface
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: plasma membrane; integral to membrane; receptor complex
Biological Process: negative regulation of B cell receptor signaling pathway; negative regulation of release of sequestered calcium ion into cytosol
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Product Notes
The FCRL5 fcrl5 (Catalog #AAA3007139) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FCRL5 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FCRL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the FCRL5 fcrl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCRL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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