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Western Blot (WB) (Western Blot (WB) analysis of LHB polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)

Rabbit LHB Polyclonal Antibody | anti-LHB antibody

LHB Polyclonal Antibody

Gene Names
LHB; CGB4; HH23; LSH-B; LSH-beta
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
LHB; Polyclonal Antibody; LHB Polyclonal Antibody; Lutropin subunit beta; Lutropin beta chain; Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta; Lutropin beta; Lutropinbeta; Lutropin-beta; LSHbeta; anti-LHB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
LHB polyclonal antibody detects endogenous levels of LHB protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
5
Applicable Applications for anti-LHB antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human LHB.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of LHB polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)

Western Blot (WB) (Western Blot (WB) analysis of LHB polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate)
Related Product Information for anti-LHB antibody
Various hormones are secreted from the anterior pituitary gland during development and growth. Lutropin, also called luteinizing hormone (LH), plays a role in spermato-genesis and ovulation by stimulating the testis and ovaries to produce steroids. LH, like many of the anterior pituitary hormones, consists of heterodimers formed from a common alpha chain and a unique beta chain. Lutropin exists in a variety of isoforms, as the hormone is proteolytically processed and metabolized throughout circulation. LH modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. Pituitary exit of LH and FSH occur via different secretion pathways, and are released spatially from the pituitary via different circulatory routes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 15kDa
NCBI Official Full Name
luteinizing hormone beta subunit (LHbeta), partial
NCBI Official Synonym Full Names
luteinizing hormone subunit beta
NCBI Official Symbol
LHB
NCBI Official Synonym Symbols
CGB4; HH23; LSH-B; LSH-beta
NCBI Protein Information
lutropin subunit beta
UniProt Protein Name
Lutropin subunit beta
UniProt Gene Name
LHB
UniProt Synonym Gene Names
Lutropin beta chain; LH-B; LSH-B; LSH-beta
UniProt Entry Name
LSHB_HUMAN

NCBI Description

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]

Uniprot Description

LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Hormone; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity; receptor binding

Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction

Disease: Fertile Eunuch Syndrome

Research Articles on LHB

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Product Notes

The LHB lhb (Catalog #AAA3006717) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LHB Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LHB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the LHB lhb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LHB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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