RAB31 blocking peptide

RAB31 Peptide

Cat. Num. AAA3006122

• Gene Names: RAB31; Rab22B
• Applications: Blocking
• Purity: Synthetic peptide RAB31. (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: RAB31; RAB31 Peptide; Ras-related protein Rab-31; Ras-related protein Rab-22B; RAB22B; RAB31 blocking peptide

• Specificity: This peptide can be used with studies using MBS3006121 RAB31 pAb.
• Purity/Purification: Synthetic peptide RAB31. (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 195

• Applicable Applications for RAB31 blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for RAB31 blocking peptide

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 31, also known as RAB22B, is a 194 amino lipid-anchored protein that localizes to the cytoplasmic side of the cell membrane and belongs to the Ras-related GTPase superfamily. Expressed at high levels in lung, brain and heart, Rab 31 may function in a similar manner to other Rab proteins, namely playing a role in protein transport.

NCBI and Uniprot Product Information

• NCBI GI #: 33589861
• NCBI GeneID: 11031
• NCBI Accession #: NP_006859.2
• NCBI GenBank Nucleotide #: NP_006859.2
• UniProt Accession #: Q13636
• NCBI Official Full Name: ras-related protein Rab-31
• NCBI Official Synonym Full Names: RAB31, member RAS oncogene family
• NCBI Official Symbol: RAB31
• NCBI Official Synonym Symbols: Rab22B
• NCBI Protein Information: ras-related protein Rab-31
• UniProt Protein Name: Ras-related protein Rab-31
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB31
• UniProt Synonym Gene Names: RAB22B
• UniProt Entry Name: RAB31_HUMAN

NCBI Description

Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009]

Uniprot Description

RAB31: Belongs to the small GTPase superfamily. Rab family

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 18p11.3

Cellular Component: phagocytic vesicle membrane; early endosome; late endosome; trans-Golgi network membrane; phagocytic vesicle

Molecular Function: GTPase activity; GDP binding; GTP binding

Biological Process: regulated secretory pathway; cellular response to insulin stimulus; receptor internalization; Golgi to plasma membrane protein transport; Rab protein signal transduction