Testing Data
(Primary: Anti-SRXN1 at 1/1000 dilution)
Rabbit SRXN1 Polyclonal Antibody | anti-SRXN1 antibody
SRXN1 Polyclonal Antibody
Gene Names
SRXN1; SRX; Npn3; SRX1; C20orf139
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
SRXN1; Polyclonal Antibody; SRXN1 Polyclonal Antibody; C20orf1392; Chromosome 20 open reading frame 139; dJ850E9.2; Npn3; Npn31; SRX1; SRXN 1; Sulfiredoxin 1; Sulfiredoxin 1 homolog (S. cerevisiae); Sulfiredoxin 1 homolog; YKL086W; SRXN1_HUMAN.; anti-SRXN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
Clonality
Polyclonal
Specificity
SRXN1 Polyclonal Antibody detects endogenous levels of SRXN1 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-SRXN1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human SRXN1:45-137/137
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
(Primary: Anti-SRXN1 at 1/1000 dilution)
Testing Data
(Primary: Anti-SRXN1 at 1/1000 dilution)
Related Product Information for anti-SRXN1 antibody
Sulfiredoxin, also designated Sulfiredoxin-1 and chromosome 20 open reading frame 139 (C20orf139), is a cytoplasmic antioxidant protein involved in signaling through catalytic reduction of oxidative modifications. It regulates peroxiredoxins (PRXs), a family of proteins that reduce hydroperoxides, by reducing the conserved cysteine from sulfinic to sulfenic acid. This impacts the role of PRX in the reduction of other downstream transcription factors and kinase signaling pathways. The Sulfiredoxin protein specifically acts on the PRDX1, PRDX2, PRDX3 and PRDX4 peroxiredoxins, but not on PRDX5 or PRDX6. Sulfiredoxin acts as a phosphotransferase and an athioltransferase and is widely expressed, with highest levels detected in lung, spleen, kidney and thymus tissues.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,259 Da
NCBI Official Full Name
sulfiredoxin-1
NCBI Official Synonym Full Names
sulfiredoxin 1
NCBI Official Symbol
SRXN1
NCBI Official Synonym Symbols
SRX; Npn3; SRX1; C20orf139
NCBI Protein Information
sulfiredoxin-1
UniProt Protein Name
Sulfiredoxin-1
Protein Family
UniProt Gene Name
SRXN1
UniProt Synonym Gene Names
C20orf139; SRX; SRX1
Uniprot Description
SRXN1: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Belongs to the sulfiredoxin family.
Protein type: EC 1.8.98.2; Oxidoreductase
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: cytosol
Molecular Function: ATP binding; oxidoreductase activity, acting on a sulfur group of donors; sulfiredoxin activity
Biological Process: response to oxidative stress
Research Articles on SRXN1
Similar Products
Product Notes
The SRXN1 srxn1 (Catalog #AAA3005559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRXN1 Polyclonal Antibody reacts with Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's SRXN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the SRXN1 srxn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRXN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
