DnaJB4 blocking peptide

DnaJB4 (R120) Peptide

Cat. Num. AAA3003327

• Applications: Blocking
• Purity: Synthetic peptide DnaJB4 (R120). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: DnaJB4; DnaJB4 (R120) Peptide; DjB4; DnaJ (Hsp40) homolog subfamily B member 4; DnaJ homolog subfamily B member 4; DnaJ like heat shock protein 40; DNAJB 4; DNAJW; Heat shock 40 kDa protein 1 homolog; Heat shock protein 40 homolog; HLJ 1; HLJ1; HSP40 homolog; DnaJB4 blocking peptide

• Specificity: This peptide can be used with studies using MBS3003326 DnaJB4 (R120) pAb.
• Purity/Purification: Synthetic peptide DnaJB4 (R120). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 337

• Applicable Applications for DnaJB4 blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for DnaJB4 blocking peptide

DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart and pancreas, and lower expression in brain, placenta and liver.

NCBI and Uniprot Product Information

• NCBI GI #: 6631085
• NCBI Accession #: NP_008965.2
• NCBI GenBank Nucleotide #: NP_008965.2
• UniProt Accession #: Q9UDY4
• NCBI Official Full Name: dnaJ homolog subfamily B member 4 isoform a
• UniProt Protein Name: DnaJ homolog subfamily B member 4
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJB4
• UniProt Synonym Gene Names: DNAJW; HLJ1; HSP40 homolog
• UniProt Entry Name: DNJB4_HUMAN

Uniprot Description

DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 1p31.1

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol

Molecular Function: protein binding; chaperone binding; unfolded protein binding

Biological Process: protein folding; response to heat; response to unfolded protein