Rat Interleukin-4 receptor subunit alpha ELISA Kit | Il4r elisa kit
Rat Interleukin-4 receptor subunit alpha ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
a receptor for the cytokine IL-4 [RGD, Feb 2006]
Uniprot Description
IL4R: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Belongs to the type I cytokine receptor family. Type 4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, cytokine
Cellular Component: extracellular space; integral to membrane; plasma membrane; receptor complex
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein heterodimerization activity
Biological Process: cytokine and chemokine mediated signaling pathway; defense response to protozoan; immune response; immunoglobulin mediated immune response; inflammatory response; negative regulation of T-helper 1 cell differentiation; ovulation; positive regulation of immunoglobulin production; positive regulation of macrophage activation; positive regulation of mast cell degranulation; positive regulation of T-helper 2 cell differentiation; production of molecular mediator of acute inflammatory response; regulation of cell proliferation; response to estrogen stimulus
Research Articles on Il4r
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Product Notes
The Rat Il4r il4r (Catalog #AAA289365) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289365 ELISA Kit recognizes Rat Il4r. It is sometimes possible for the material contained within the vial of "Interleukin-4 receptor subunit alpha, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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