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Metalloproteinase inhibitor 1 Protein | TIMP1 protein

Metalloproteinase inhibitor 1

Gene Names
Timp1; EPA; Clgi; Timp; TIMP-1; TPA-S1
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
Metalloproteinase inhibitor 1; Timp; Timp-1; Collagenase inhibitor 16C8 fibroblast; Erythroid-potentiating activity; TPA-S1; TPA-induced protein; Tissue inhibitor of metalloproteinases 1; EPA; TIMP-1; TIMP1 protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid
Sequence Length
205
Applicable Applications for TIMP1 protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
Tags
His
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.
Product Categories/Family for TIMP1 protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,628 Da
NCBI Official Full Name
metalloproteinase inhibitor 1 isoform a
NCBI Official Synonym Full Names
tissue inhibitor of metalloproteinase 1
NCBI Official Symbol
Timp1
NCBI Official Synonym Symbols
EPA; Clgi; Timp; TIMP-1; TPA-S1
NCBI Protein Information
metalloproteinase inhibitor 1
UniProt Protein Name
Metalloproteinase inhibitor 1
UniProt Gene Name
Timp1
UniProt Synonym Gene Names
Timp; Timp-1; EPA; TIMP-1

Uniprot Description

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.

Research Articles on TIMP1

Similar Products

Product Notes

The TIMP1 timp1 (Catalog #AAA2888718) is a Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Metalloproteinase inhibitor 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array. Researchers should empirically determine the suitability of the TIMP1 timp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Metalloproteinase inhibitor 1, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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