Typical Testing Data/Standard Curve (for reference only)
Mouse Myc box-dependent-interacting protein 1 ELISA Kit | Bin1 elisa kit
Mouse Myc box-dependent-interacting protein 1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
BIN1: May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy type 2 (CNM2). A congenital muscle disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers. 11 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Cytoskeletal; Tumor suppressor; Adaptor/scaffold
Cellular Component: axon; cytoplasm; I band; membrane; nerve terminal; nucleus; synaptic vesicle; T-tubule; Z disc
Molecular Function: GTPase binding; identical protein binding; protein binding; protein complex binding; protein heterodimerization activity; tau protein binding
Biological Process: cell differentiation; endocytosis; multicellular organismal development; muscle cell differentiation; positive regulation of apoptosis; positive regulation of astrocyte differentiation; positive regulation of endocytosis; positive regulation of GTPase activity; regulation of endocytosis; regulation of neuron differentiation
Research Articles on Bin1
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Product Notes
The Mouse Bin1 bin1 (Catalog #AAA2886924) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886924 ELISA Kit recognizes Mouse Bin1. It is sometimes possible for the material contained within the vial of "Myc box-dependent-interacting protein 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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