Mouse Alpha-crystallin A chain ELISA Kit | Cryaa elisa kit
Mouse Alpha-crystallin A chain ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes subunit a, one of two subunits of alpha-crystallin, which is a high molecular weight, soluble aggregate and is a member of the small heat shock protein (sHSP) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. It acts as a molecular chaperone and is the major protein in the eye lens, maintaining the transparency and refractive index of the lens. In mouse, deficiency in this gene is associated with smaller lenses and eyes and with increasing lens opacity with age. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
CRYA1: a major structural protein of the eye lens. A member of the small heat shock protein (sHSP, also known as the HSP20) family. Alpha-A is preferentially restricted to the lens.
Protein type: Heat shock protein; Chaperone
Cellular Component: cytoplasm; nucleus
Molecular Function: identical protein binding; metal ion binding; protein binding; structural constituent of eye lens; unfolded protein binding
Biological Process: actin filament organization; apoptosis; camera-type eye development; embryonic camera-type eye morphogenesis; lens development in camera-type eye; lens morphogenesis in camera-type eye; microtubule-based process; mitochondrion organization and biogenesis; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of cell growth; positive regulation of protein amino acid phosphorylation; protein folding; protein homooligomerization; response to hydrogen peroxide; response to hypoxia; tubulin folding
Research Articles on Cryaa
Similar Products
Product Notes
The Mouse Cryaa cryaa (Catalog #AAA2886769) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886769 ELISA Kit recognizes Mouse Cryaa. It is sometimes possible for the material contained within the vial of "Alpha-crystallin A chain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.