Typical Testing Data/Standard Curve (for reference only)
Mouse Angiotensinogen ELISA Kit | Agt elisa kit
Mouse Angiotensinogen ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
angiotensin: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin-1 (angiotensin 1-10). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2 (angiotensin 1- 8). Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3 (angiotensin 2-8), angiotensin-4 (angiotensin 3-8). Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2 or from angiotensin-1 by MME (neprilysin). Angiotensin 1-9 is cleaved from angiotensin-1 by ACE2. Genetic variations in AGT are a cause of susceptibility to essential hypertension (EHT). Essential hypertension is a condition in which blood pressure is consistently higher than normal with no identifiable cause. Defects in AGT are a cause of renal tubular dysgenesis (RTD). RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype). Belongs to the serpin family.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: cytoplasm; extracellular space
Molecular Function: angiotensin receptor binding; hormone activity; serine-type endopeptidase inhibitor activity; sodium channel regulator activity; type 1 angiotensin receptor binding; type 2 angiotensin receptor binding
Biological Process: activation of NF-kappaB-inducing kinase; angiotensin mediated drinking behavior; angiotensin mediated regulation of renal output; angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure; artery smooth muscle contraction; astrocyte activation; blood vessel development; brain renin-angiotensin system; cell surface receptor linked signal transduction; cell-matrix adhesion; cellular sodium ion homeostasis; cytokine secretion; drinking behavior; establishment of blood-nerve barrier; excretion; extracellular matrix organization and biogenesis; fibroblast proliferation; G-protein coupled receptor protein signaling pathway; hormone metabolic process; kidney development; negative regulation of angiogenesis; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis; negative regulation of tissue remodeling; ovarian follicle rupture; peristalsis; phospholipase C activation; positive regulation of blood pressure; positive regulation of catalytic activity; positive regulation of cell proliferation; positive regulation of cellular protein metabolic process; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of fatty acid biosynthetic process; positive regulation of fibroblast proliferation; positive regulation of MAPKKK cascade; positive regulation of multicellular organism growth; positive regulation of nitric oxide biosynthetic process; positive regulation of organ growth; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of superoxide release; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; regulation of apoptosis; regulation of blood pressure; regulation of calcium ion transport; regulation of gene expression; regulation of heart rate; regulation of inflammatory response; regulation of long-term neuronal synaptic plasticity; regulation of norepinephrine secretion; regulation of systemic arterial blood pressure by circulatory renin-angiotensin; regulation of transmission of nerve impulse; renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure; renal system process; renin-angiotensin regulation of aldosterone production; response to cold; response to muscle activity involved in regulation of muscle adaptation; response to salt stress; smooth muscle cell differentiation; smooth muscle cell proliferation; stress-activated MAPK cascade; ureteric bud branching; vasoconstriction; vasodilation
Research Articles on Agt
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Product Notes
The Mouse Agt agt (Catalog #AAA2885708) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885708 ELISA Kit recognizes Mouse Agt. It is sometimes possible for the material contained within the vial of "Angiotensinogen, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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