Rat Protein kinase C alpha type ELISA Kit | Prkca elisa kit

Rat Protein kinase C alpha type ELISA Kit

Cat. Num. AAA2884943

• Reactivity: Rat
• Synonyms: Protein kinase C alpha type; Rat Protein kinase C alpha type ELISA Kit; PKC-A; PKC-alpha; Prkca; Pkca; 2.7.11.13; Prkca elisa kit

• Reactivity: Rat
• Sequence Length: 672

• Assay Type: Sandwich
• Detection Range: 0.312-20 ng/mL
• Sensitivity: 0.172 ng/mL
• Intra-Assay CV: <=4.8%
• Inter-Assay CV: <=9.2%
• Recovery: 98%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 125552
• NCBI GeneID: 24680
• UniProt Accession #: P05696
• Molecular Weight: 76,792 Da
• NCBI Official Full Name: Protein kinase C alpha type
• UniProt Protein Name: Protein kinase C alpha type
• Protein Family: Protein kinase
• UniProt Gene Name: Prkca
• UniProt Synonym Gene Names: Pkca; PKC-A; PKC-alpha
• UniProt Entry Name: KPCA_RAT

Uniprot Description

PKCA: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic and receptors. Classical PKCs are calcium-dependent enzymes that are activated by phosphatidylserine, diacylglycerol and phorbol esters. Contains a pseudo-substrate autoinhibitory domain that binds to the catalytic domain preventing its activation in the absence of cofactors or activators.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, AGC; Kinase, protein; Oncoprotein; EC 2.7.11.13; AGC group; PKC family; Alpha subfamily

Cellular Component: apical part of cell; axon; cell soma; cytoplasm; cytosol; dendrite; endoplasmic reticulum; intracellular; lipid raft; membrane; mitochondrial membrane; mitochondrion; neuron projection; nucleus; perinuclear region of cytoplasm; photoreceptor outer segment; plasma membrane; protein complex

Molecular Function: ATP binding; calcium-dependent protein kinase C activity; enzyme binding; protein binding; protein kinase activity; protein kinase C activity; protein serine/threonine kinase activity; zinc ion binding

Biological Process: aging; angiogenesis; apoptosis; cell adhesion; cellular calcium ion homeostasis; central nervous system neuron axonogenesis; chondrocyte differentiation; establishment of protein localization; inactivation of MAPK activity; induction of positive chemotaxis; learning and/or memory; negative regulation of cell proliferation; negative regulation of glucose import; negative regulation of heart contraction; negative regulation of insulin receptor signaling pathway; negative regulation of protein amino acid phosphorylation; negative regulation of protein kinase activity; negative regulation of translation; neutrophil chemotaxis; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell adhesion; positive regulation of cell migration; positive regulation of endothelial cell proliferation; positive regulation of exocytosis; positive regulation of inflammatory response; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of macrophage differentiation; positive regulation of mitotic cell cycle; positive regulation of protein amino acid phosphorylation; positive regulation of smooth muscle cell proliferation; positive regulation of synaptogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of muscle contraction; regulation of peptidyl-tyrosine phosphorylation; regulation of receptor-mediated endocytosis; regulation of the force of heart contraction; response to antibiotic; response to corticosterone stimulus; response to estradiol stimulus; response to ethanol; response to mechanical stimulus; response to organic cyclic substance; response to peptide hormone stimulus; response to reactive oxygen species; response to toxin