Typical Testing Data/Standard Curve (for reference only)
Mouse P2X purinoceptor 7 ELISA Kit | P2rx7 elisa kit
Mouse P2X purinoceptor 7 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
P2X7: a receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis by macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Alternatively spliced variants encoding different isoforms have been identified. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. Phosphorylation results in its inactivation.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, ligand-gated; Receptor, misc.
Cellular Component: cell soma; external side of plasma membrane; integral to membrane; integral to nuclear inner membrane; integral to plasma membrane; intercellular junction; membrane; neuromuscular junction; plasma membrane; synapse
Molecular Function: ATP binding; ATP-gated cation channel activity; channel activity; ion channel activity; lipopolysaccharide binding; protein binding; purinergic nucleotide receptor activity; receptor activity
Biological Process: activation of MAPK activity; bleb formation; calcium ion transport; cation transport; cell morphogenesis; cell volume homeostasis; cellular response to extracellular stimulus; ceramide biosynthetic process; collagen metabolic process; cytolysis; defense response to Gram-positive bacterium; gene expression; homeostasis of number of cells within a tissue; inflammatory response; ion transport; membrane budding; membrane depolarization; membrane protein ectodomain proteolysis; mitochondrion organization and biogenesis; multicellular organismal protein catabolic process; NAD transport; negative regulation of bone resorption; negative regulation of cell volume; negative regulation of MAPKKK cascade; phagolysosome formation; phospholipid scrambling; phospholipid transfer to membrane; phospholipid translocation; plasma membrane organization and biogenesis; pore complex biogenesis; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of catalytic activity; positive regulation of cytokine secretion; positive regulation of gamma-aminobutyric acid secretion; positive regulation of glutamate secretion; positive regulation of glycolysis; positive regulation of interleukin-1 alpha secretion; positive regulation of interleukin-1 beta production; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-6 production; positive regulation of MAPKKK cascade; positive regulation of mitochondrial depolarization; positive regulation of ossification; positive regulation of prostaglandin secretion; positive regulation of protein amino acid phosphorylation; positive regulation of protein secretion; positive regulation of T cell mediated cytotoxicity; programmed cell death; protein amino acid phosphorylation; protein oligomerization; protein processing; release of sequestered calcium ion into cytosol; response to ATP; response to bacterium; response to calcium ion; response to drug; response to electrical stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to organic cyclic substance; response to organic substance; response to zinc ion; sensory perception of pain; skeletal morphogenesis; synaptic vesicle exocytosis; T cell homeostasis; T cell proliferation; transport
Research Articles on P2rx7
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Product Notes
The Mouse P2rx7 p2rx7 (Catalog #AAA2884788) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884788 ELISA Kit recognizes Mouse P2rx7. It is sometimes possible for the material contained within the vial of "P2X purinoceptor 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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