Typical Testing Data/Standard Curve (for reference only)
Mouse Beta-1 adrenergic receptor ELISA Kit | Adrb1 elisa kit
Mouse Beta-1 adrenergic receptor ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
Uniprot Description
ADRB1: a GPCR-coupled 7 transmembrane receptor that binds epinephrine and norepinephrine with approximately equal affinity. Mediates the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Interacts with PIST and PSD-95. Localized at the plasma membrane and in the Golgi upon PIST overexpression. Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Cellular Component: cytoplasm; early endosome; endosome; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane
Molecular Function: adrenoceptor activity; alpha-2A adrenergic receptor binding; beta1-adrenergic receptor activity; dopamine binding; drug binding; epinephrine binding; G-protein coupled receptor activity; norepinephrine binding; PDZ domain binding; protein binding; protein heterodimerization activity; Ras guanyl-nucleotide exchange factor activity; receptor signaling protein activity; signal transducer activity
Biological Process: apoptosis; brown fat cell differentiation; cell-cell signaling; diet induced thermogenesis; fear response; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; glycogen catabolic process; heat generation; lipid homeostasis; memory; negative regulation of multicellular organism growth; negative regulation of smooth muscle contraction; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure; positive regulation of adenylate cyclase activity; positive regulation of apoptosis; positive regulation of cAMP biosynthetic process; positive regulation of GTPase activity; positive regulation of heart contraction; positive regulation of heart rate; positive regulation of heart rate by epinephrine-norepinephrine; positive regulation of saliva secretion; positive regulation of systemic arterial blood pressure; positive regulation of the force of heart contraction by epinephrine-norepinephrine; positive regulation of the force of heart contraction by norepinephrine; protein localization in organelle; regulation of calcium ion transport; regulation of inhibitory postsynaptic membrane potential; response to cold; Rho protein signal transduction; sensory perception of pain; signal transduction; wound healing
Research Articles on Adrb1
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Product Notes
The Mouse Adrb1 adrb1 (Catalog #AAA2884085) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884085 ELISA Kit recognizes Mouse Adrb1. It is sometimes possible for the material contained within the vial of "Beta-1 adrenergic receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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