Rat ATPase WRNIP1 (WRNIP1) ELISA Kit | WRNIP1 elisa kit

Rat ATPase WRNIP1 (WRNIP1) ELISA Kit

Cat. Num. AAA286661

• Gene Names: Wrnip1; Whip; Wrnip
• Reactivity: Rat
• Synonyms: ATPase WRNIP1 (WRNIP1); Rat ATPase WRNIP1 (WRNIP1) ELISA Kit; FLJ22526; RP11-420G6.2; WHIP; bA420G6.2; Werner helicase interacting protein; putative helicase RUVBL; WRNIP1 elisa kit

• Reactivity: Rat
• Specificity: This assay has high sensitivity and excellent specificity for detection of Rat WRNIP1. No significant cross-reactivity or interference between Rat WRNIP1 and analogues was observed.
• Sequence Length: 660

• Assay Type: Quantitive Sandwich
• Samples: Serum, Plasma, Other Biological Fluids
• Detection Wavelength: 450 nm
• Intra-assay Precision (Precision within an assay): Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
• Inter-assay Precision (Precision between assays): Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
• CV (%): = SD/meanX100
• Intra-Assay: CV
• Inter-Assay: CV
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for WRNIP1 elisa kit

This assay employs a two-site sandwich ELISA to quantitate WRNIP1 in samples. An antibody specific for WRNIP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any WRNIP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for WRNIP1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of WRNIP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 27229310
• NCBI GeneID: 282835
• NCBI Accession #: NP_758835.1
• NCBI GenBank Nucleotide #: NM_172332.2
• UniProt Accession #: Q8CG07
• Molecular Weight: 71,934 Da
• NCBI Official Full Name: ATPase WRNIP1
• NCBI Official Synonym Full Names: Werner helicase interacting protein 1
• NCBI Official Symbol: Wrnip1
• NCBI Official Synonym Symbols: Whip; Wrnip
• NCBI Protein Information: ATPase WRNIP1
• UniProt Protein Name: ATPase WRNIP1
• Protein Family: ATPase
• UniProt Gene Name: Wrnip1

NCBI Description

human homolog binds WRN, a member of the RecQ family of DNA helicases that is mutated in Werner syndrome; may contribute to the premature aging phenotype in Werner syndrome [RGD, Feb 2006]

Uniprot Description

Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.