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Human Interleukin-17 ELISA Kit | IL17RD elisa kit

Human Interleukin-17 receptor D (IL17RD) ELISA Kit

Gene Names
IL17RD; SEF; HH18; IL-17RD; IL17RLM
Reactivity
Human
Synonyms
Interleukin-17; Human Interleukin-17 receptor D (IL17RD) ELISA Kit; DKFZp434N1928; FLJ35755; IL-17RD; IL17RLM; MGC133309; SEF;; IL17RD elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human IL17RD. No significant cross-reactivity or interference between Human IL17RD and analogues was observed.
Sequence Length
9
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for IL17RD elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate IL17RD in samples. An antibody specific for IL17RD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyIL17RD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL17RD is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL17RD bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
79,463 Da
NCBI Official Full Name
interleukin-17 receptor D isoform b
NCBI Official Synonym Full Names
interleukin 17 receptor D
NCBI Official Symbol
IL17RD
NCBI Official Synonym Symbols
SEF; HH18; IL-17RD; IL17RLM
NCBI Protein Information
interleukin-17 receptor D
UniProt Protein Name
Interleukin-17 receptor D
Protein Family
UniProt Gene Name
IL17RD
UniProt Synonym Gene Names
IL17RLM; SEF; IL-17 receptor D; IL-17RD; hSef

NCBI Description

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

Uniprot Description

IL17RD: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: Golgi apparatus; Golgi membrane; integral component of plasma membrane; nucleoplasm

Molecular Function: interleukin-17 receptor activity

Biological Process: cytokine-mediated signaling pathway; MAPK cascade

Disease: Hypogonadotropic Hypogonadism 18 With Or Without Anosmia; Hypogonadotropic Hypogonadism 7 With Or Without Anosmia

Research Articles on IL17RD

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Product Notes

The Human IL17RD il17rd (Catalog #AAA285676) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA285676 ELISA Kit recognizes Human IL17RD. It is sometimes possible for the material contained within the vial of "Interleukin-17, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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