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Porcine Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) ELISA Kit | ACADM elisa kit

Porcine Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) ELISA Kit

Gene Names
ACADM; MCAD; ACAD1; MCADH
Reactivity
Porcine
Synonyms
Medium-chain specific acyl-CoA dehydrogenase; mitochondrial (ACADM); Porcine Medium-chain specific acyl-CoA dehydrogenase; mitochondrial (ACADM) ELISA Kit; ACADM elisa kit
Ordering
For Research Use Only!
Reactivity
Porcine
Sequence Length
425
Preparation and Storage
Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
34
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,020 Da
NCBI Official Full Name
medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform b
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
NCBI Official Symbol
ACADM
NCBI Official Synonym Symbols
MCAD; ACAD1; MCADH
NCBI Protein Information
medium-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
UniProt Protein Name
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
UniProt Gene Name
ACADM
UniProt Synonym Gene Names
MCAD
UniProt Entry Name
ACADM_HUMAN

NCBI Description

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ACADM: This enzyme is specific for acyl chain lengths of 4 to 16. Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD). It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy. Belongs to the acyl-CoA dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.8.7; Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - propanoate; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: mitochondrion; mitochondrial matrix; axon; nucleus

Molecular Function: acyl-CoA dehydrogenase activity; identical protein binding; FAD binding

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; medium-chain fatty acid catabolic process; cellular lipid metabolic process; medium-chain fatty acid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; carnitine biosynthetic process

Disease: Acyl-coa Dehydrogenase, Medium-chain, Deficiency Of

Research Articles on ACADM

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Product Notes

The Porcine ACADM acadm (Catalog #AAA2600223) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2600223 ELISA Kit recognizes Porcine ACADM. It is sometimes possible for the material contained within the vial of "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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