Rabbit NPTN Polyclonal Antibody | anti-NPTN antibody

NPTN Polyclonal Antibody

Cat. Num. AAA2566766

• Gene Names: NPTN; GP55; GP65; SDR1; np55; np65; SDFR1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity purification
• Synonyms: NPTN; Polyclonal Antibody; NPTN Polyclonal Antibody; GP55; GP65; SDFR1; SDR1; np55; np65; anti-NPTN antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1mg/mL (varies by lot)

• Applicable Applications for anti-NPTN antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human NPTN (NP_0594291)
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines using NPTN Polyclonal Antibody at dilution of 1:1000.)

Related Product Information for anti-NPTN antibody

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-NPTN antibody

Polyclonal Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 6912646
• NCBI GeneID: 27020
• NCBI Accession #: NP_036560.1
• NCBI GenBank Nucleotide #: NM_012428.3
• UniProt Accession #: Q9Y639; Q17R52; Q59EJ9; Q6NVX7; Q9Y640; B2RAL7; B7Z4D3; B7ZLL2
• Molecular Weight: 43,931 Da
• NCBI Official Full Name: neuroplastin isoform b
• NCBI Official Synonym Full Names: neuroplastin
• NCBI Official Symbol: NPTN
• NCBI Official Synonym Symbols: GP55; GP65; SDR1; np55; np65; SDFR1
• NCBI Protein Information: neuroplastin; SDR-1; stromal cell-derived receptor 1; stromal cell derived factor receptor 1
• UniProt Protein Name: Neuroplastin
• Protein Family: Neuroplastin
• UniProt Gene Name: NPTN
• UniProt Synonym Gene Names: SDFR1; SDR1; SDR-1
• UniProt Entry Name: NPTN_HUMAN

NCBI Description

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

Uniprot Description

neuroplastin: Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 15q22

Cellular Component: presynaptic membrane; cell surface; integral to membrane

Molecular Function: cell adhesion molecule binding; transmembrane receptor protein tyrosine kinase activity; ATP binding; type 1 fibroblast growth factor receptor binding

Biological Process: elevation of cytosolic calcium ion concentration; peptidyl-tyrosine phosphorylation; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of protein amino acid phosphorylation; homophilic cell adhesion; positive regulation of long-term neuronal synaptic plasticity; transmembrane receptor protein tyrosine kinase signaling pathway