Mouse anti-Mouse CD64 Antibody | anti-CD64 antibody

PE/Cyanine5 Anti-Mouse CD64 Antibody[X54-5/7.1]

Cat. Num. AAA2559339

• Reactivity: Mouse
• Applications: Flow Cytometry, Functional Assay
• Synonyms: CD64; PE/Cyanine5 Anti-Mouse CD64 Antibody[X54-5/7.1]; Fcg1; Fcgr1; FcRI; IgG Fc receptor I; anti-CD64 antibody

• Host: Mouse
• Reactivity: Mouse
• Isotype: Mouse IgG1, kappa
• Clone Number: X54-5/7.1
• Form/Format: Liquid; PBS with 0.05% Proclin300, 1% BSA
• Sequence Length: 404

• Applicable Applications for anti-CD64 antibody: Flow Cytometry (FC/FACS)
• Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 muL of antibody per test (million cells in 100 ul staining volume or per 100 ul of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
• Isotype Control: PE/Cyanine5 Mouse IgG1, kappa Isotype Control[MOPC-21][Product MBS2557735]
• Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
• Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
• Preparation and Storage: Keep as concentrated solution and store at 2~8°C, protected from prolonged exposure to light. Do not freeze.; Avoid repeated freeze/thaw cycles..; This product is guaranteed up to one year from purchase.

Fluorophore

(Conjugation: PE/Cyanine5)

Flow Cytometry (FC/FACS)

(C57BL/6 murine bone marrow cells are stained with PE/Cyanine5 Anti-Mouse CD64 Antibody and FITC Anti- Mouse CD11b Antibody.)

Related Product Information for anti-CD64 antibody

CD64 is a 72 kD single chain type I glycoprotein also known as Fc?RI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-? stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

NCBI and Uniprot Product Information

• NCBI GI #: 182888429
• UniProt Accession #: P26151
• NCBI Official Full Name: Fc receptor, IgG, high affinity I
• UniProt Protein Name: High affinity immunoglobulin gamma Fc receptor I
• UniProt Gene Name: Fcgr1
• UniProt Synonym Gene Names: Fcg1; IgG Fc receptor I; FcRI
• UniProt Entry Name: FCGR1_MOUSE

Uniprot Description

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; integral to membrane; plasma membrane; lipid raft; external side of plasma membrane

Molecular Function: leukotriene receptor binding; IgG binding; IgG receptor activity

Biological Process: receptor-mediated endocytosis; regulation of immune response; immune system process; positive regulation of type III hypersensitivity; phagocytosis, recognition; antigen processing and presentation of exogenous antigen; antibody-dependent cellular cytotoxicity; cell surface receptor linked signal transduction; response to bacterium; positive regulation of type IIa hypersensitivity; positive regulation of phagocytosis; defense response to bacterium; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; positive regulation of phagocytosis, engulfment; phagocytosis, engulfment