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SDS-PAGE

Serum Amyloid P Component Active Protein | Apcs active protein

Recombinant Mouse APCS/SAP Protein (His Tag)

Gene Names
Apcs; Sap
Purity
> 95 % as determined by SDS-PAGE
Synonyms
Serum Amyloid P Component; Recombinant Mouse APCS/SAP Protein (His Tag); APCS; PTX2; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P; MGC88159; PTX2serum amyloid P-component; SAP pentaxin-related; Apcs active protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 10 mM Tris, 10,< NaH2PO4, 0.2 M NaCl, 1 mM EDTA, 0.5 M sucrose, 5% Trehalose, pH 8.4, 5% Mannitol, and 0.01% Tween-80
Sequence Positions
Gln21-Asp224
Species
Mouse
Tag
C-6His
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom. Do not mix by vortex. It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV-Vis.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20°C to -80°C.
Reconstituted protein solution can be stored at 4°C to 8°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for up to 3 months.

SDS-PAGE

SDS-PAGE
Related Product Information for Apcs active protein
Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 24.9 kDa
Actual Protein Molecular Mass: 28-32 kDa
NCBI Official Full Name
serum amyloid P-component
NCBI Official Synonym Full Names
serum amyloid P-component
NCBI Official Symbol
Apcs
NCBI Official Synonym Symbols
Sap
NCBI Protein Information
serum amyloid P-component
UniProt Protein Name
Serum amyloid P-component
UniProt Gene Name
Apcs
UniProt Synonym Gene Names
Ptx2; Sap; SAP

Research Articles on Apcs

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Product Notes

The Apcs apcs (Catalog #AAA2556795) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Gln21-Asp224. It is sometimes possible for the material contained within the vial of "Serum Amyloid P Component, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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