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Western Blot (WB) (Western Blot analysis of HepG2, A431 cells and Rat brain using EF-Tu Polyclonal Antibody at dilution of 1:500)

Rabbit anti-Human, Rat TUFM Polyclonal Antibody | anti-TUFM antibody

TUFM Polyclonal Antibody

Gene Names
TUFM; P43; EFTU; COXPD4; EF-TuMT
Reactivity
Human, Rat
Applications
Western Blot
Purity
Affinity Purification
Synonyms
TUFM; Polyclonal Antibody; TUFM Polyclonal Antibody; COXPD4; EF Tu; EF TuMT; EF-Tu; EF-TuMT; EFTu; EFTU; EFTuMT; Elongation factor Tu; Elongation factor Tu mitochondrial; mitochondrial; P43; Tu translation elongation factor mitochondrial; Tufm; anti-TUFM antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
2 mg/mL (varies by lot)
Sequence Length
452
Applicable Applications for anti-TUFM antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant Human Elongation factor Tu, mitochondrial protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of HepG2, A431 cells and Rat brain using EF-Tu Polyclonal Antibody at dilution of 1:500)

Western Blot (WB) (Western Blot analysis of HepG2, A431 cells and Rat brain using EF-Tu Polyclonal Antibody at dilution of 1:500)
Related Product Information for anti-TUFM antibody
TUFM, also named as Elongation factor Tu, mitochondrial, is a 452 amino acid protein, which contains 1 tr-type G (guanine nucleotide-binding) domain and belongs to the TRAFAC class translation factor GTPase superfamily. TUFM localizes in the Mitochondrion and promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Product Categories/Family for anti-TUFM antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 50kDa
Observed: 50kDa
NCBI Official Full Name
elongation factor Tu, mitochondrial isoform 1
NCBI Official Synonym Full Names
Tu translation elongation factor, mitochondrial
NCBI Official Symbol
TUFM
NCBI Official Synonym Symbols
P43; EFTU; COXPD4; EF-TuMT
NCBI Protein Information
elongation factor Tu, mitochondrial
UniProt Protein Name
Elongation factor Tu, mitochondrial
UniProt Gene Name
TUFM
UniProt Synonym Gene Names
EF-Tu

NCBI Description

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]

Uniprot Description

Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

Research Articles on TUFM

Similar Products

Product Notes

The TUFM tufm (Catalog #AAA2554016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TUFM Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TUFM can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TUFM tufm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TUFM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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