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Western Blot (WB)
(Western Blot analysis of Human fetal brain tissue using CDC42/RHO/RAC Polyclonal Antibody at dilution of 1:200)
Rho-GTPase Antibody Kit
Rho-GTPase Antibody Sampler Kit
Applications
Western Blot
Synonyms
Rho-GTPase; Rho-GTPase Antibody Sampler Kit; Rho-GTPase antibody kit
Applicable Applications for Rho-GTPase antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of Human fetal brain tissue using CDC42/RHO/RAC Polyclonal Antibody at dilution of 1:200)
Western Blot (WB)
(Western Blot analysis of Human fetal brain tissue using CDC42/RHO/RAC Polyclonal Antibody at dilution of 1:200)
Western Blot (WB)
(Western Blot analysis of HeLa cells with Rac1/2/3/CDC42 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of HeLa cells with Rac1/2/3/CDC42 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of HepG2 cells using Rho A Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of HepG2 cells using Rho A Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of Mouse brain and fetal brain tissue using RHOB Polyclonal Antibody at dilution of 1:800)
Western Blot (WB)
(Western Blot analysis of Mouse brain and fetal brain tissue using RHOB Polyclonal Antibody at dilution of 1:800)
Western Blot (WB)
(Western Blot analysis of Human fetal brain tissue using RHOC Polyclonal Antibody at dilution of 1:300)
Western Blot (WB)
(Western Blot analysis of Human fetal brain tissue using RHOC Polyclonal Antibody at dilution of 1:300)
Related Product Information for Rho-GTPase antibody kit
Background: The Rho family of small GTPases, including Rho, Rac, and cdc42, act as molecular switches to regulate processes such as cell migration, adhesion, proliferation and differentiation. RhoA, RhoB and RhoC are all highly homologous but appear to have divergent biological functions. The best characterized of these proteins, RhoA, regulates acomysin contractility, cytokinesis, focal adhesion assembly and cell polarity. Mammalian Rac exists as three isoforms (Rac1, Rac2 and Rac3) that show high sequence similarity. Well-characterized Rac1 and cdc42 are ubiquitously expressed and play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, and cell growth and development. Phosphorylation of Rac1 at a putative Akt site (Ser71) may limit Rac1 activity through inhibition of GTP binding. Rac2 is expressed in cells of hematopoietic origin, while Rac3 is highly expressed in brain and in many other tissues. The Vav family of guanine-nucleotide exchange factors mediates activation of Rho/Rac family small GTPases. Negative regulation of Rho-activity members of the p190 RhoGAP family (p190-A and p190-B) may be controlled by Src phosphorylation of Tyr residues, activating the p190 GAP domain. Furthermore, Rho GDP dissociation inhibitor (RhoGDI) associates with Rho/Rac to negatively regulate nucleotide exchange membrane localization.
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Product Notes
The Rho-GTPase (Catalog #AAA2550019) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Rho-GTPase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Rho-GTPase for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rho-GTPase, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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