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SDS-PAGE

HAAO / 3-HAO recombinant protein

Recombinant Rat HAAO / 3-HAO Protein (His tag)

Purity
> 90 % as determined by SDS-PAGE.
Synonyms
HAAO / 3-HAO; Recombinant Rat HAAO / 3-HAO Protein (His tag); HAAO; 3-HAO; HAAO / 3-HAO recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 90 % as determined by SDS-PAGE.
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
286
Application Notes
The recombinant rat Haao consists 304 amino acids and predicts a molecular mass of 34.8 kDa.
Predicted N Terminal
Met
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for HAAO / 3-HAO recombinant protein
A DNA sequence encoding the rat Haao (NP_064461.1) (Met1-Gly286) was expressed with a polyhistidine tag at the N-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,582 Da
NCBI Official Full Name
3-hydroxyanthranilate 3,4-dioxygenase
NCBI Official Synonym Full Names
3-hydroxyanthranilate 3,4-dioxygenase
NCBI Official Symbol
Haao
NCBI Protein Information
3-hydroxyanthranilate 3,4-dioxygenase
UniProt Protein Name
3-hydroxyanthranilate 3,4-dioxygenase
UniProt Gene Name
Haao
UniProt Synonym Gene Names
3-HAO; HAD

NCBI Description

enzyme responsible for the synthesis of quinolinic acid [RGD, Feb 2006]

Uniprot Description

HAAO: Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. Belongs to the 3-HAO family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tryptophan; EC 1.13.11.6; Oxidoreductase

Chromosomal Location of Human Ortholog: 6q12

Cellular Component: cytoplasm; cytosol; mitochondrial membrane

Molecular Function: 3-hydroxyanthranilate 3,4-dioxygenase activity; ferrous iron binding; iron ion binding; oxygen binding

Biological Process: quinolinate metabolic process; response to cadmium ion; response to zinc ion

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Product Notes

The HAAO / 3-HAO haao (Catalog #AAA2547272) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant rat Haao consists 304 amino acids and predicts a molecular mass of 34.8 kDa. Researchers should empirically determine the suitability of the HAAO / 3-HAO haao for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAAO / 3-HAO, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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