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Western Blot (WB) (Western blot analysis of extracts of various cells, using CDC42EP3 antibody.)

Rabbit anti-Human, Rat CDC42EP3 Polyclonal Antibody | anti-CDC42EP3 antibody

CDC42EP3 Polyclonal Antibody

Gene Names
CDC42EP3; UB1; CEP3; BORG2
Reactivity
Human, Rat
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
CDC42EP3; Polyclonal Antibody; CDC42EP3 Polyclonal Antibody; UB1; CEP3; BORG2; anti-CDC42EP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Sequence Length
254
Applicable Applications for anti-CDC42EP3 antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of human CDC42EP3
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cells, using CDC42EP3 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cells, using CDC42EP3 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28kDa
NCBI Official Full Name
cdc42 effector protein 3
NCBI Official Synonym Full Names
CDC42 effector protein 3
NCBI Official Symbol
CDC42EP3
NCBI Official Synonym Symbols
UB1; CEP3; BORG2
NCBI Protein Information
cdc42 effector protein 3
UniProt Protein Name
Cdc42 effector protein 3
Protein Family
UniProt Gene Name
CDC42EP3
UniProt Synonym Gene Names
BORG2; CEP3
UniProt Entry Name
BORG2_HUMAN

NCBI Description

This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

CDC42EP3: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Belongs to the BORG/CEP family.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: actin cytoskeleton; cytoplasm; cytosol; plasma membrane

Molecular Function: cytoskeletal regulatory protein binding; GTP-Rho binding; GTPase activator activity

Biological Process: positive regulation of actin filament polymerization; positive regulation of pseudopodium formation; regulation of cell shape; Rho protein signal transduction; signal transduction

Research Articles on CDC42EP3

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Product Notes

The CDC42EP3 cdc42ep3 (Catalog #AAA2540893) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDC42EP3 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDC42EP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the CDC42EP3 cdc42ep3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC42EP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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