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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using LEPR antibody.)

Rabbit anti-Human LEPR Polyclonal Antibody | anti-LEPR antibody

LEPR Antibody

Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
LEPR; Polyclonal Antibody; LEPR Antibody; OBR; OB-R; CD295; LEP-R; anti-LEPR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
57
Applicable Applications for anti-LEPR antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
A synthetic peptide of human LEPR
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1833 / sc-1832 / sc-33978 / sc-1834 / sc-8325
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using LEPR antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using LEPR antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer tissue using LEPR antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon cancer tissue using LEPR antibody.)
Related Product Information for anti-LEPR antibody
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
6,605 Da
NCBI Official Full Name
LEPR, partial
UniProt Protein Name
LEPR
Protein Family
UniProt Gene Name
LEPR
UniProt Entry Name
O97779_LOXAF

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Product Notes

The LEPR lepr (Catalog #AAA2528984) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LEPR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LEPR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the LEPR lepr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LEPR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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