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Testing Data

Rabbit ISG20 Polyclonal Antibody | anti-ISG20 antibody

ISG20 Antibody

Gene Names
ISG20; CD25; HEM45
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
ISG20; Polyclonal Antibody; ISG20 Antibody; CD25; HEM45; anti-ISG20 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
181
Applicable Applications for anti-ISG20 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:5000
Immunogen
Fusion protein of ISG20
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9,199 Da
NCBI Official Full Name
interferon-stimulated gene 20 kDa protein isoform a
NCBI Official Synonym Full Names
interferon stimulated exonuclease gene 20kDa
NCBI Official Symbol
ISG20
NCBI Official Synonym Symbols
CD25; HEM45
NCBI Protein Information
interferon-stimulated gene 20 kDa protein; estrogen-regulated transcript 45 protein; promyelocytic leukemia nuclear body-associated protein ISG20
UniProt Protein Name
Interferon-stimulated gene 20 kDa protein
UniProt Gene Name
ISG20
UniProt Synonym Gene Names
HEM45
UniProt Entry Name
ISG20_HUMAN

Uniprot Description

ISG20: Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses. Belongs to the exonuclease superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.13.1; Deoxyribonuclease; Nucleolus; Ribonuclease

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: nucleoplasm; Cajal body; PML body; cytoplasm; nucleolus; nucleus

Molecular Function: exoribonuclease II activity; 3'-5'-exoribonuclease activity; U1 snRNA binding; metal ion binding; exonuclease activity; single-stranded DNA specific 3'-5' exodeoxyribonuclease activity; U2 snRNA binding

Biological Process: cell proliferation; negative regulation of viral genome replication; cytokine and chemokine mediated signaling pathway; response to virus; RNA catabolic process; DNA catabolic process, exonucleolytic; defense response to virus; rRNA processing

Research Articles on ISG20

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Product Notes

The ISG20 isg20 (Catalog #AAA2526622) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ISG20 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ISG20 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:5000. Researchers should empirically determine the suitability of the ISG20 isg20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISG20, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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