Rabbit anti-Human HOXA4 Polyclonal Antibody | anti-HOXA4 antibody

HOXA4 Polyclonal Antibody

Cat. Num. AAA2525887

• Gene Names: HOXA4; HOX1; HOX1D
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: HOXA4; Polyclonal Antibody; HOXA4 Polyclonal Antibody; HOX1; HOX1D; anti-HOXA4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.05% sodium azide, 50% glycerol, pH7.3

• Applicable Applications for anti-HOXA4 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:25-1:100
• Preparation and Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HOXA4 Polyclonal Antibody at dilution 1:20)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using HOXA4 Polyclonal Antibody at dilution 1:20)

Related Product Information for anti-HOXA4 antibody

Background/Introduction: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation

Product Categories/Family for anti-HOXA4 antibody

Epigenetics

NCBI and Uniprot Product Information

• NCBI GI #: 148613882
• NCBI GeneID: 3201
• NCBI Accession #: NP_002132.3
• NCBI GenBank Nucleotide #: NM_002141.4
• UniProt Accession #: Q00056; O43366; A4D180
• NCBI Official Full Name: homeobox protein Hox-A4
• NCBI Official Synonym Full Names: homeobox A4
• NCBI Official Symbol: HOXA4
• NCBI Official Synonym Symbols: HOX1; HOX1D
• NCBI Protein Information: homeobox protein Hox-A4; Dfd-like protein; Hox-1.4-like protein; homeo box A4; homeobox protein Hox-1.4; homeobox protein Hox-1D
• UniProt Protein Name: Homeobox protein Hox-A4
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXA4
• UniProt Synonym Gene Names: HOX1D
• UniProt Entry Name: HXA4_HUMAN

NCBI Description

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXA4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'. Belongs to the Antp homeobox family. Deformed subfamily.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7p15.2

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: anterior/posterior pattern formation; anatomical structure morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent; embryonic skeletal morphogenesis