Rabbit TRAF3IP3 Polyclonal Antibody | anti-TRAF3IP3 antibody

Rabbit Polyclonal (IgG) to Human TRAF3IP3

Cat. Num. AAA248843

• Gene Names: TRAF3IP3; T3JAM
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: TRAF3IP3; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human TRAF3IP3; Anti-TRAF3IP3 Antibody (aa251-300) IHC-plus; DJ434O14.3; TRAF3 interacting protein 3; TRAF3-interacting protein 3; T3JAM; Human TRAF3IP3; anti-TRAF3IP3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: T3JAM Antibody detects endogenous levels of total T3JAM protein.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
• Sequence Length: 531

• Applicable Applications for anti-TRAF3IP3 antibody: Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA (1:20000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000)
• Target Species: Human
• Immunogen Description: Synthetic peptide from human T3JAM (aa251-300).
• Immunogen: TRAF3IP3 antibody was raised against synthetic peptide from human T3JAM (aa251-300).
• Antigen Modification: aa251-300
• Preparation and Storage: Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-TRAF3IP3 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of HeLa cells, using T3JAM Antibody. The picture on the right is treated with the synthesized peptide.)

Western Blot (WB)

(Western blot of extracts from Jurkat cells, using T3JAM Antibody. The lane on the right is treated with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 13435127
• NCBI GeneID: 80342
• NCBI Accession #: NP_079504.1
• NCBI GenBank Nucleotide #: NM_025228.1
• UniProt Accession #: Q9Y228; Q2YDB5; Q4VY06; Q7Z706; A1L464; A6NIU9
• Molecular Weight: 40,674 Da
• NCBI Official Full Name: TRAF3 interacting protein 3
• NCBI Official Synonym Full Names: TRAF3 interacting protein 3
• NCBI Official Symbol: TRAF3IP3
• NCBI Official Synonym Symbols: T3JAM
• NCBI Protein Information: TRAF3-interacting JNK-activating modulator; TRAF3 interacting Jun N terminal kinase (JNK) activating modulator
• UniProt Protein Name: TRAF3-interacting JNK-activating modulator
• Protein Family: TRAF3-interacting JNK-activating modulator
• UniProt Gene Name: TRAF3IP3
• UniProt Synonym Gene Names: T3JAM
• UniProt Entry Name: T3JAM_HUMAN

NCBI Description

The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Uniprot Description

TRAF3IP3: May function as an adapter molecule that regulates TRAF3-mediated JNK activation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: integral to membrane

Molecular Function: protein binding