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Immunohistochemistry (IHC) (Anti-TAC3 / Tachykinin antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit anti-Human TAC3 / Tachykinin Polyclonal Antibody | anti-TAC3 antibody

Rabbit Polyclonal to Human TAC3 / Tachykinin

Gene Names
TAC3; NKB; HH10; NKNB; PRO1155; ZNEUROK1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
TAC3 / Tachykinin; Polyclonal Antibody; Rabbit Polyclonal to Human TAC3 / Tachykinin; Anti-TAC3 / Tachykinin Antibody (aa53-83) IHC-plus; TAC3; Gamma tachykinin 3; Neuromedin K; Neurokinin beta; NKB; NKNB; Neurokinin B; ZNEUROK1; Tachykinin 3; Tachykinin-3; HH10; Preprotachykinin B; PRO1155; Tachykinin; Human TAC3; anti-TAC3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human Tachykinin
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
121
Applicable Applications for anti-TAC3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (1:10 - 1:75), WB (1:1000)
Target Species
Human
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human TAC3.
Immunogen Type
Synthetic peptide
Immunogen
TAC3 / Tachykinin antibody was raised against kLH-conjugated synthetic peptide from internal region of human TAC3.
Antigen Modification
aa53-83
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Anti-TAC3 / Tachykinin antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TAC3 / Tachykinin antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TAC3 / Tachykinin antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TAC3 / Tachykinin antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Western Blot (WB)

(TAC3 Antibody (Center) Western blot of Jurkat cell line lysates (35 ug/lane). This demonstrates the TAC3 antibody detected the TAC3 protein (arrow).)

Western Blot (WB) (TAC3 Antibody (Center) Western blot of Jurkat cell line lysates (35 ug/lane). This demonstrates the TAC3 antibody detected the TAC3 protein (arrow).)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,358 Da
NCBI Official Full Name
tachykinin-3 isoform 1 preproprotein
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Symbol
TAC3
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1
NCBI Protein Information
tachykinin-3; neurokinin b; neuromedin K; gamma tachykinin 3; preprotachykinin B; preprotachykinin-B
UniProt Protein Name
Tachykinin-3
Protein Family
UniProt Gene Name
TAC3
UniProt Synonym Gene Names
NKNB; NKB
UniProt Entry Name
TKNK_HUMAN

NCBI Description

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; receptor binding

Biological Process: tachykinin signaling pathway; neuropeptide signaling pathway; female pregnancy

Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia

Research Articles on TAC3

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Product Notes

The TAC3 tac3 (Catalog #AAA248745) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human TAC3 / Tachykinin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAC3 / Tachykinin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (1:10 - 1:75), WB (1:1000). Researchers should empirically determine the suitability of the TAC3 tac3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAC3 / Tachykinin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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