Immunohistochemistry (IHC)
(Anti-GPR12 / GPCR12 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit GPR12 Polyclonal Antibody | anti-GPR12 antibody
Rabbit Polyclonal to Human GPR12
Gene Names
GPR12; GPCR12; GPCR21; PPP1R84
Reactivity
Gibbon, Bovine, Gorilla, Hamster, Horse, Human, Mouse, Pig, Rabbit, RatPredicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GPR12; Polyclonal Antibody; Rabbit Polyclonal to Human GPR12; Anti-GPR12 Antibody (Extracellular Domain) IHC-plus; G protein-coupled receptor 12; G-protein coupled receptor 12; GPCR12; GPCR21; Human GPR12; anti-GPR12 antibody
Host
Rabbit
Reactivity
Gibbon, Bovine, Gorilla, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity)
Predicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GPR12 / GPCR12. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR6 (53%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
334
Applicable Applications for anti-GPR12 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (1.2 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR12 / GPCR12. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
GPR12 antibody was raised against synthetic 15 amino acid peptide from 2nd extracellular domain of human GPR12 / GPCR12. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%); Monkey, Dog, Bat, Opossum, Turkey, Chicken, Xenopus (93%); Platypus, Pufferfish (87%); Stickleback (80%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-GPR12 / GPCR12 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPR12 / GPCR12 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GPR12 antibody
GPR12 has been identified as a constitutively active Lysophospholipid/Lysosphingolipid receptor.
Product Categories/Family for anti-GPR12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,730 Da
NCBI Official Full Name
G-protein coupled receptor 12
NCBI Official Synonym Full Names
G protein-coupled receptor 12
NCBI Official Symbol
GPR12
NCBI Official Synonym Symbols
GPCR12; GPCR21; PPP1R84
NCBI Protein Information
G-protein coupled receptor 12; protein phosphatase 1, regulatory subunit 84
UniProt Protein Name
G-protein coupled receptor 12
Protein Family
UniProt Gene Name
GPR12
UniProt Entry Name
GPR12_HUMAN
Uniprot Description
GPR12: Promotes neurite outgrowth and blocks myelin inhibition in neurons. Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q12
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity; phosphatidylcholine binding
Biological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway
Research Articles on GPR12
Similar Products
Product Notes
The GPR12 gpr12 (Catalog #AAA247780) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GPR12 reacts with Gibbon, Bovine, Gorilla, Hamster, Horse, Human, Mouse, Pig, Rabbit, Rat Predicted Reactivity: Monkey, Bat, Dog, Chicken, Xenopus (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's GPR12 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (1.2 ug/ml). Researchers should empirically determine the suitability of the GPR12 gpr12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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