Immunohistochemistry (IHC)
(Anti-SLC4A2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit SLC4A2 / AE2 Polyclonal Antibody | anti-SLC4A2 antibody
Rabbit Polyclonal to Human SLC4A2 / AE2
Gene Names
SLC4A2; AE2; HKB3; BND3L; NBND3; EPB3L1
Reactivity
Reactivity: Human, Mouse, Rat, Dog, Hamster, Horse, Pig, RabbitPredicted Reactivity: Monkey, Bovine, Guinea pig
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
SLC4A2 / AE2; Polyclonal Antibody; Rabbit Polyclonal to Human SLC4A2 / AE2; Anti-SLC4A2 / AE2 Antibody (N-Terminus) IHC-plus; SLC4A2; Anion exchange protein 2; AE 2; Anion exchanger 2; Anion exchanger 2 type a; Anion exchanger 2 type b1; Anion exchanger 2 type b2; BND3L; EPB3L1; AE2; HKB3; MPB3L; Anion exchanger type 2; Erythrocyte band 3; NBND3; Human SLC4A2; anti-SLC4A2 antibody
Host
Rabbit
Reactivity
Reactivity: Human, Mouse, Rat, Dog, Hamster, Horse, Pig, Rabbit
Predicted Reactivity: Monkey, Bovine, Guinea pig
Predicted Reactivity: Monkey, Bovine, Guinea pig
Clonality
Polyclonal
Specificity
Human SLC4A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, less than 0.1% sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
1241
Applicable Applications for anti-SLC4A2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: MBS247729 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS247729 was determined to be 10 ug/ml.
Usage: Immunohistochemistry: MBS247729 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS247729 was determined to be 10 ug/ml.
Target
Human SLC4A2 / AE2
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from N-Terminus of human SLC4A2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Galago, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Horse, Rabbit, Pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
SLC4A2 / AE2 antibody was raised against synthetic 18 amino acid peptide from N-Terminus of human SLC4A2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Galago, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Horse, Rabbit, Pig (100%); Monkey, Bovine, Guinea pig (94%); Elephant (89%); Bat, Opossum (83%).
Antigen Modification
N-Terminus
Preparation and Storage
Upon arrival: Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze thaw cycles.
Immunohistochemistry (IHC)
(Anti-SLC4A2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SLC4A2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SLC4A2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-SLC4A2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-SLC4A2 antibody
Slc4A2 belongs to the family of plasma membrane anion exchangers that maintain the chloride and bicarbonate homeostasis within cells and in the extracellular fluid.
Product Categories/Family for anti-SLC4A2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
136,247 Da
NCBI Official Full Name
anion exchange protein 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 4 (anion exchanger), member 2
NCBI Official Symbol
SLC4A2
NCBI Official Synonym Symbols
AE2; HKB3; BND3L; NBND3; EPB3L1
NCBI Protein Information
anion exchange protein 2; AE 2; anion exchanger 2 type a; anion exchanger 2 type b1; anion exchanger 2 type b2; solute carrier family 4 member 2; non-erythroid band 3-like protein; erythrocyte membrane protein band 3-like 1
UniProt Protein Name
Anion exchange protein 2
Protein Family
UniProt Gene Name
SLC4A2
UniProt Synonym Gene Names
AE2; EPB3L1; HKB3; MPB3L; AE 2; Anion exchanger 2; BND3L
UniProt Entry Name
B3A2_HUMAN
Uniprot Description
SLC4A2: Plasma membrane anion exchange protein of wide distribution. Belongs to the anion exchanger (TC 2.A.31) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 7q36.1
Cellular Component: focal adhesion; membrane; integral to plasma membrane; basolateral plasma membrane; plasma membrane
Molecular Function: inorganic anion exchanger activity; chloride transmembrane transporter activity; anion transmembrane transporter activity
Biological Process: bicarbonate transport; regulation of intracellular pH; ion transport; transmembrane transport; anion transport
Research Articles on SLC4A2
Similar Products
Product Notes
The SLC4A2 slc4a2 (Catalog #AAA247729) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SLC4A2 / AE2 reacts with Reactivity: Human, Mouse, Rat, Dog, Hamster, Horse, Pig, Rabbit Predicted Reactivity: Monkey, Bovine, Guinea pig and may cross-react with other species as described in the data sheet. AAA Biotech's SLC4A2 / AE2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 ug/ml) Usage: Immunohistochemistry: MBS247729 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS247729 was determined to be 10 ug/ml. Researchers should empirically determine the suitability of the SLC4A2 slc4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC4A2 / AE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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