Immunohistochemistry (IHC)
(Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE))
Rabbit HRH4 / Histamine H4 Receptor Polyclonal Antibody | anti-HRH4 antibody
Rabbit Polyclonal to Human HRH4 / Histamine H4 Receptor
Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
Immunohistochemistry (IHC)
(Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE))
Transfection
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Transfection
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Transfection Control
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Transfection Control
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NCBI and Uniprot Product Information
NCBI Description
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Uniprot Description
H4R: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 18q11.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: histamine receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of MAPKKK cascade; inflammatory response
Research Articles on HRH4
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Product Notes
The HRH4 hrh4 (Catalog #AAA247300) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human HRH4 / Histamine H4 Receptor reacts with Human Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's HRH4 / Histamine H4 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), ELISA (EIA). ELISA, ICC, IHC-P (5 - 10 ug/ml). Researchers should empirically determine the suitability of the HRH4 hrh4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HRH4 / Histamine H4 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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