Goat anti-Mouse MCPT4 / Mcp4 Polyclonal Antibody | anti-MCPT4 antibody

Goat Polyclonal to Mouse MCPT4 / Mcp4

Cat. Num. AAA247149

• Gene Names: Mcpt4; Mcp4; Mcp-4; MMCP-4; MMCP-4A; MMCP-4B
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: MCPT4 / Mcp4; Polyclonal Antibody; Goat Polyclonal to Mouse MCPT4 / Mcp4; Anti-MCPT4 / Mcp4 Antibody (Internal) IHC-plus; MCPT4; MCP-4; Mast cell protease 4; MCP4; Mcpt4; Mmcp4; MMCP-4A; MMCP-4B; MMCP-4; Mouse MCPT4; Mcp4; anti-MCPT4 antibody

• Host: Goat
• Reactivity: Mouse
• Clonality: Polyclonal
• Specificity: Mouse MCPT4.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 246

• Applicable Applications for anti-MCPT4 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:64000), IHC-P (3.75 ug/ml); Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments gave bands at approx. 40kDa and 15kDa in Mouse Skeletal Muscle lysates after 0.01 ug/ml antibody staining. Please note that currently we cannot find an ex...
• Target Species: Mouse
• Immunogen Description: Synthetic peptide C-KLQKKAKETPSVN from an internal region of mouse MCPT4 (NP_034909.2). Percent identity with other species by BLAST analysis: Mouse (100%).
• Immunogen Type: Synthetic peptide
• Immunogen: MCPT4 / Mcp4 antibody was raised against synthetic peptide C-KLQKKAKETPSVN from an internal region of mouse MCPT4 (NP_034909.2). Percent identity with other species by BLAST analysis: Mouse (100%).
• Antigen Modification: Internal
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-MCPT4 antibody IHC of mouse skeletal muscle, mast cell. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Product Categories/Family for anti-MCPT4 antibody

Family: Protease; Subfamily: Serine S1

NCBI and Uniprot Product Information

• NCBI GI #: 114205406
• NCBI GeneID: 17227
• NCBI Accession #: NP_034909.2
• NCBI GenBank Nucleotide #: NM_010779.2
• UniProt Accession #: P21812; Q9EPQ9; Q9EQT2
• Molecular Weight: 27,204 Da
• NCBI Official Full Name: mast cell protease 4
• NCBI Official Synonym Full Names: mast cell protease 4
• NCBI Official Symbol: Mcpt4
• NCBI Official Synonym Symbols: Mcp4; Mcp-4; MMCP-4; MMCP-4A; MMCP-4B
• NCBI Protein Information: mast cell protease 4; MSMCP; myonase; serosal mast cell protease
• UniProt Protein Name: Mast cell protease 4
• Protein Family: Mast cell protease
• UniProt Gene Name: Mcpt4
• UniProt Synonym Gene Names: mMCP-4
• UniProt Entry Name: MCPT4_MOUSE

Uniprot Description

Mcpt4: Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta- protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Belongs to the peptidase S1 family. Granzyme subfamily.

Protein type: EC 3.4.21.-; Protease

Cellular Component: extracellular space; intracellular

Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity

Biological Process: regulation of angiotensin levels in blood; protein processing; proteolysis