Mouse anti-Human RETN / Resistin Monoclonal Antibody | anti-RETN antibody

Mouse Monoclonal (IgG2b,k) to Human RETN / Resistin

Cat. Num. AAA246475

• Gene Names: RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Protein A Purified
• Synonyms: RETN / Resistin; Monoclonal Antibody; Mouse Monoclonal (IgG2b; k) to Human RETN / Resistin; Anti-RETN / Resistin Antibody IHC-plus; RETN; ADSF; Fizz3; Resistin; RETN1; Xcp1; RSTN; Found in inflammatory zone 3; HXCP1; Resistin delta2; Human RETN; anti-RETN antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Specificity: Human Resistin
• Purity/Purification: Protein A Purified
• Form/Format: Lyophilized from PBS. Sourced in TCS.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 108

• Applicable Applications for anti-RETN antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (10 ug/ml), WB (0.2 - 0.4 ug/ml); Usage: Immunohistochemistry: in an IHC-plus antibody, validated by our pathologists for use in IHC against formalin-fixed, paraffin-embedded human tissues (IHC validation procedure). A concentration of 10 ug/ml is recommended. ELISA: In a sandwich...
• Target Species: Human
• Resuspension Liquid Description: Reconstitute with sterile water
• Immunogen Description: E.coli derived recombinant Human Resistin.
• Immunogen Type: Cell extract
• Immunogen: RETN / Resistin antibody was raised against e.coli derived recombinant Human Resistin.
• Preparation and Storage: Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8 degree C. Aliquot and freeze at -20 degree C for long term storage. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-RETN / Resistin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western Blot (non-reducing) of Resistin antibody)

Western Blot (WB)

(Western Blot (reducing) of Resistin antibody)

ELISA (EIA)

(Sandwich ELISA of Resistin antibody)

NCBI and Uniprot Product Information

• NCBI GI #: 9966777
• NCBI GeneID: 56729
• NCBI Accession #: NP_065148.1
• NCBI GenBank Nucleotide #: NM_020415.3
• UniProt Accession #: Q9HD89; Q540D9; Q76B53; D6W649
• Molecular Weight: 8,686 Da
• NCBI Official Full Name: resistin
• NCBI Official Synonym Full Names: resistin
• NCBI Official Symbol: RETN
• NCBI Official Synonym Symbols: ADSF; RSTN; XCP1; FIZZ3; RETN1
• NCBI Protein Information: resistin; resistin delta2; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; cysteine-rich secreted protein A12-alpha-like 2; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1
• UniProt Protein Name: Resistin
• Protein Family: Resistin
• UniProt Gene Name: RETN
• UniProt Synonym Gene Names: FIZZ3; HXCP1; RSTN; ADSF
• UniProt Entry Name: RETN_HUMAN

NCBI Description

This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Uniprot Description

resistin: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Belongs to the resistin/FIZZ family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; nucleus

Molecular Function: hormone activity

Biological Process: fat cell differentiation; response to mechanical stimulus; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of synaptic transmission; aging; response to insulin stimulus

Disease: Diabetes Mellitus, Noninsulin-dependent