Immunohistochemistry (IHC)
(Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human Neuropeptide Y / NPY Monoclonal Antibody | anti-NPY antibody
Mouse Monoclonal [clone 3H2] (IgG1,k) to Human Neuropeptide Y / NPY
Usage: Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein.
Immunohistochemistry (IHC)
(Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
ELISA (EIA)
(Detection limit for recombinant GST tagged NPY is approximately 3 ng/ml as a capture antibody.)
ELISA (EIA)
(Detection limit for recombinant GST tagged NPY is approximately 3 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Uniprot Description
NPY: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Belongs to the NPY family.
Protein type: Hormone; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7p15.1
Cellular Component: Golgi apparatus; extracellular space; cell; extracellular region
Molecular Function: G-protein coupled receptor activity; neuropeptide hormone activity; neuropeptide Y receptor binding; calcium channel regulator activity; receptor binding
Biological Process: blood circulation; behavior; adult feeding behavior; cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; neuropeptide signaling pathway; calcium ion transport; positive regulation of appetite; regulation of blood pressure; digestion; regulation of appetite; feeding behavior; cerebral cortex development; cell motility; neurite development; central nervous system neuron development
Research Articles on NPY
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Product Notes
The NPY npy (Catalog #AAA246043) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 3H2] (IgG1,k) to Human Neuropeptide Y / NPY reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Neuropeptide Y / NPY can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1:500 - 1:1000) Usage: Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein. Researchers should empirically determine the suitability of the NPY npy for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuropeptide Y / NPY, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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