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Immunohistochemistry (IHC) (Anti-SLC16A7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Goat SLC16A7 / MCT2 Polyclonal Antibody | anti-SLC16A7 antibody

Goat Polyclonal to Human SLC16A7 / MCT2

Gene Names
SLC16A7; MCT2
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
SLC16A7 / MCT2; Polyclonal Antibody; Goat Polyclonal to Human SLC16A7 / MCT2; Anti-SLC16A7 / MCT2 Antibody (C-Terminus) IHC-plus; SLC16A7; MCT 2; Monocarboxylate transporter 2; MCT2; Human SLC16A7; anti-SLC16A7 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human SLC16A7.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
478
Applicable Applications for anti-SLC16A7 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:128000), IHC-P (2.5 - 3.75 ug/ml), WB (1:128000, 1 - 3 ug/ml)
Target Species
Human
Immunogen Description
Synthetic peptide C-SNAQSVTSERETNI from the C-terminus of human SLC16A7 (NP_004722.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset (93%); Monkey (86%).
Immunogen Type
Synthetic peptide
Immunogen
SLC16A7 / MCT2 antibody was raised against synthetic peptide C-SNAQSVTSERETNI from the C-terminus of human SLC16A7 (NP_004722.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset (93%); Monkey (86%).
Antigen Modification
C-Terminus
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-SLC16A7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Immunohistochemistry (IHC) (Anti-SLC16A7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Western Blot (WB)

(Antibody (1 ug/ml) staining of A549 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) (Antibody (1 ug/ml) staining of A549 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Product Categories/Family for anti-SLC16A7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,200 Da
NCBI Official Full Name
monocarboxylate transporter 2
NCBI Official Synonym Full Names
solute carrier family 16 (monocarboxylate transporter), member 7
NCBI Official Symbol
SLC16A7
NCBI Official Synonym Symbols
MCT2
NCBI Protein Information
monocarboxylate transporter 2; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
UniProt Protein Name
Monocarboxylate transporter 2
UniProt Gene Name
SLC16A7
UniProt Synonym Gene Names
MCT2; MCT 2
UniProt Entry Name
MOT2_HUMAN

NCBI Description

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

SLC16A7: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: pyruvate secondary active transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity; pyruvate transmembrane transporter activity

Biological Process: transmembrane transport

Research Articles on SLC16A7

Similar Products

Product Notes

The SLC16A7 slc16a7 (Catalog #AAA243657) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human SLC16A7 / MCT2 reacts with Gibbon, Gorilla, Human Predicted Reactivity: Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's SLC16A7 / MCT2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:128000), IHC-P (2.5 - 3.75 ug/ml), WB (1:128000, 1 - 3 ug/ml). Researchers should empirically determine the suitability of the SLC16A7 slc16a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC16A7 / MCT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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