Immunohistochemistry (IHC)
(Anti-LASS5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Rabbit LASS5 Polyclonal Antibody | anti-LASS5 antibody
Rabbit Polyclonal to Human LASS5
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Immunohistochemistry (IHC)
(Anti-LASS5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-LASS5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of LASS5 in Human Brain cells with LASS5 antibody at 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of LASS5 in Human Brain cells with LASS5 antibody at 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of LASS5 in human brain tissue with LASS5 antibody at 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of LASS5 in human brain tissue with LASS5 antibody at 20 ug/ml.)
Western Blot (WB)
(Western blot of LASS5 in SK-N-SH lysate with LASS5 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.)
Western Blot (WB)
(Western blot of LASS5 in SK-N-SH lysate with LASS5 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.
Protein type: Transferase; DNA-binding; Membrane protein, integral; EC 2.3.1.24; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q13.12
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; endoplasmic reticulum; integral to membrane
Molecular Function: DNA binding; sphingosine N-acyltransferase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process
Research Articles on LASS5
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Product Notes
The LASS5 cers5 (Catalog #AAA242295) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human LASS5 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LASS5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the LASS5 cers5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LASS5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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