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Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit MCAD/ACADM Polyclonal Antibody | anti-MCAD/ACADM antibody

Anti-MCAD/ACADM Antibody

Gene Names
ACADM; MCAD; ACAD1; MCADH
Reactivity
Human
Predicted: Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
MCAD/ACADM; Polyclonal Antibody; Anti-MCAD/ACADM Antibody; Rabbit Polyclonal (IgG) to Human MCAD/ACADM; ACADM; ACAD1; MCAD; MCADH; anti-MCAD/ACADM antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human MCAD/ACADM
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Sequence Length
421
Applicable Applications for anti-MCAD/ACADM antibody
Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC: 1:50-1:200
IHC-P: 1:100
WB: 1:500-1:2000
Immunogen
Recombinant protein of human ACADM
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of extracts of HepG2 cells.)

Western Blot (WB) (Western blot analysis of extracts of HepG2 cells.)

Western Blot (WB)

(Western blot analysis of extracts of HepG2 cell line, using ACADM antibody.)

Western Blot (WB) (Western blot analysis of extracts of HepG2 cell line, using ACADM antibody.)
Related Product Information for anti-MCAD/ACADM antibody
MCAD/ACADM is the medium-chain specific (C4 to C12 straight chain)acyl-Coenzyme A dehydrogenase. the homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway.Defects in this gene cause medium-chain acyl-CoA dehydrogenasedeficiency, a disease characterized by hepatic dysfunction, fastinghypoglycemia, and encephalopathy, which can result in infantile death.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
34
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,020 Da
NCBI Official Full Name
medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform a
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase medium chain
NCBI Official Symbol
ACADM
NCBI Official Synonym Symbols
MCAD; ACAD1; MCADH
NCBI Protein Information
medium-chain specific acyl-CoA dehydrogenase, mitochondrial
UniProt Protein Name
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
UniProt Gene Name
ACADM
UniProt Synonym Gene Names
MCAD

NCBI Description

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

Research Articles on MCAD/ACADM

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Product Notes

The MCAD/ACADM acadm (Catalog #AAA2401320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MCAD/ACADM Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MCAD/ACADM can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC: 1:50-1:200 IHC-P: 1:100 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MCAD/ACADM acadm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCAD/ACADM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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