Immunohistochemistry (IHC)
(Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE))
Goat SH3GL1/EEN Polyclonal Antibody | anti-SH3GL1/EEN antibody
Anti-SH3GL1/EEN Antibody (aa261-272)
Gene Names
SH3GL1; EEN; CNSA1; SH3P8; SH3D2B
Reactivity
HumanPredicted: Dog, Monkey
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
SH3GL1/EEN; Polyclonal Antibody; Anti-SH3GL1/EEN Antibody (aa261-272); Mouse Monoclonal [clone 2F5] (IgG1) to Human SH3GL1/EEN; SH3GL1; CNSA1; Endophilin-A2; Endophilin-2; Extra 11-19 leukemia fusion; SH3-domain GRB2-like 1; SH3 domain protein 2B; EEN; EEN fusion partner of MLL; SH3D2B; SH3P8; anti-SH3GL1/EEN antibody
Host
Goat
Reactivity
Human
Predicted: Dog, Monkey
Predicted: Dog, Monkey
Clonality
Polyclonal
Specificity
Human SH3GL1/Endophilin-A2.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Sequence Length
368
Applicable Applications for anti-SH3GL1/EEN antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:32000
IHC-P: 5 ug/ml
WB: 0.3-1 ug/ml
IHC-P: 5 ug/ml
WB: 0.3-1 ug/ml
Immunogen
Synthetic peptide C-EPFDLGEPEQSN from an internal region of human SH3GL1/Endophilin-A2 (NP_003016.1). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Panda, Dog (100%); Gorilla, Bat, Pig (92%); Hamster (83%).
Conjugation
Unconjugated
Epitope
aa261-272
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human, Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE))
Western Blot (WB)
(SH3GL1 antibody (0.3 ug/ml) staining of K562 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(SH3GL1 antibody (0.3 ug/ml) staining of K562 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-SH3GL1/EEN antibody
SH3GL1/EEN is a member of the endophilin family of Src homology 3domain-containing proteins. the encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,519 Da
NCBI Official Full Name
endophilin-A2 isoform 1
NCBI Official Synonym Full Names
SH3 domain containing GRB2 like 1, endophilin A2
NCBI Official Symbol
SH3GL1
NCBI Official Synonym Symbols
EEN; CNSA1; SH3P8; SH3D2B
NCBI Protein Information
endophilin-A2
UniProt Protein Name
Endophilin-A2
UniProt Gene Name
SH3GL1
UniProt Synonym Gene Names
CNSA1; SH3D2B; EEN
NCBI Description
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Uniprot Description
Implicated in endocytosis. May recruit other proteins to membranes with high curvature ().
Research Articles on SH3GL1/EEN
Similar Products
Product Notes
The SH3GL1/EEN sh3gl1 (Catalog #AAA2400958) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-SH3GL1/EEN Antibody (aa261-272) reacts with Human Predicted: Dog, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GL1/EEN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:32000 IHC-P: 5 ug/ml WB: 0.3-1 ug/ml. Researchers should empirically determine the suitability of the SH3GL1/EEN sh3gl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GL1/EEN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
