Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Anti-Midkine antibody IHC of human small intestine, goblet cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Rabbit anti-Human MDK/Midkine Polyclonal Antibody | anti-MDK antibody

Anti-MDK/Midkine Antibody

Gene Names
MDK; MK; ARAP; NEGF2
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
MDK/Midkine; Polyclonal Antibody; Anti-MDK/Midkine Antibody; Rabbit Polyclonal to Human MDK/Midkine; MDK; ARAP; MK; MK1; NEGF2; Midkine; Retinoic acid inducible factor; anti-MDK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human Midkine
Purity/Purification
Immunoaffinity Purified
Form/Format
Lyophilized from PBS, pH 7.2
Sequence Length
143
Applicable Applications for anti-MDK antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
IHC-P: 5 ug/ml
WB: 0.1-0.2 ug/ml
Immunogen
E Coli derived recombinant Human Midkine.
Conjugation
Unconjugated
Resuspension Liquid
Sterile water
Preparation and Storage
Store Lyophilized at room temperature up to 1 month.
Reconstituted for up to two weeks at 2-8 degree C.
Aliquot and freeze at -20 degree C for long term storage.
Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Anti-Midkine antibody IHC of human small intestine, goblet cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-Midkine antibody IHC of human small intestine, goblet cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

ELISA (EIA)

ELISA (EIA)
Related Product Information for anti-MDK antibody
Developmentally regulated, secreted growth factor homologous topleiotrophin (PTN), which has heparin binding activity. Binds anaplasticlymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed bythe activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,512 Da
NCBI Official Full Name
midkine isoform a
NCBI Official Synonym Full Names
midkine
NCBI Official Symbol
MDK
NCBI Official Synonym Symbols
MK; ARAP; NEGF2
NCBI Protein Information
midkine
UniProt Protein Name
Midkine
Protein Family
UniProt Gene Name
MDK
UniProt Synonym Gene Names
MK1; NEGF2; MK; ARAP

NCBI Description

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Uniprot Description

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development ().

Research Articles on MDK

Similar Products

Product Notes

The MDK mdk (Catalog #AAA2400759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MDK/Midkine Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MDK/Midkine can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 0.5-2 ug/ml IHC-P: 5 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the MDK mdk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MDK/Midkine, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.