Mouse WC1 Monoclonal Antibody | anti-WC1 antibody
MOUSE ANTI BOVINE WC1:FITC
Gene Names
CD163L1; WC1; WC1.1
Applications
Flow Cytometry, Functional Assay
Synonyms
WC1; Monoclonal Antibody; MOUSE ANTI BOVINE WC1:FITC; anti-WC1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
CC101
Form/Format
FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1 mg/ml (varies by lot)
Sequence Length
1436
Applicable Applications for anti-WC1 antibody
Flow cytometry (FC/FACS)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation
1% Bovine Serum Albumin
Preparation
Immunogen
Con A stimulated bovine lymphocytes
Buffer Solution
Buffer Solution
Target Species
Bovine
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-WC1 antibody
Mouse anti bovine WC1, clone CC101 recognizes a subset of WC1+ T-cells expressing the WC1.1 isoform (MacHugh et al. 1993). The bovine WC1 cell surface antigen is expressed by a population of gamma/delta TCR expression cells which lack CD2, CD4 and CD8 but express CD3. WC1 expression appears to be heterogeneous and antibodies of this cluster show differing reaction patterns (Crocker et al. 1993). Mouse anti bovine WC1, clone CC101 immunoprecipitates a 215 kDa molecule from bovine cells, and also recognizes the swine homolog of WC1, which is a 180kDa molecule. In pigs the 180kDa molecule is expressed by a gamma/delta TCR positive T-cell population that also lack CD2, CD4 and CD8 (Carr et al. 1994).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
154,197 Da
NCBI Official Full Name
antigen WC1.1
NCBI Official Synonym Full Names
CD163 molecule-like 1
NCBI Official Symbol
CD163L1
NCBI Official Synonym Symbols
WC1; WC1.1
NCBI Protein Information
antigen WC1.1; WC1.1 molecule
UniProt Protein Name
Antigen WC1.1
UniProt Entry Name
WC11_BOVIN
Uniprot Description
CD163L1: a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: membrane; extracellular region
Molecular Function: scavenger receptor activity
Biological Process: receptor-mediated endocytosis
Research Articles on WC1
Similar Products
Product Notes
The WC1 (Catalog #AAA215140) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's WC1 can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10. Researchers should empirically determine the suitability of the WC1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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