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Mouse ASTROVIRUS Monoclonal Antibody | anti-ORF2 antibody

MOUSE ANTI ASTROVIRUS

Applications
ELISA, Immunoprecipitation
Synonyms
ASTROVIRUS; Monoclonal Antibody; MOUSE ANTI ASTROVIRUS; anti-ORF2 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8E7
Specificity
This item specifically recognises a genus specific epitope within the viral capsid protein of all human astrovirus serotypes. This item does not cross-react with rotavirus (SA11), SRSV, adenovirus type 2, 40 and 41, norwalk virus 8F11, Hawaii virus, coxsackievirus types A9 and B2, calcivirus and snow mountain virus.

Astrovirus is a non-enveloped single-stranded RNA virus of the Astroviridae family, and a common causative agent of gastroenteritis in the young and adults.
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
796
Applicable Applications for anti-ORF2 antibody
ELISA (EIA), Immunoprecipitation (IP)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen
Astrovirus type 2 expressed in LLC MK2 cells.
Buffer Solution
Phosphate buffered saline
Target Species
Viral
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Related Product Information for anti-ORF2 antibody
MBS214478 specifically recognises a genus specific epitope within the viral capsid protein of all human astrovirus serotypes. MBS214478 does not cross-react with rotavirus (SA11), SRSV, adenovirus type 2, 40 and 41, norwalk virus 8F11, Hawaii virus, coxsackievirus types A9 and B2, calcivirus and snow mountain virus. Astrovirus is a non-enveloped single-stranded RNA virus of the Astroviridae family, and a common causative agent of gastroenteritis in the young and adults.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
NCBI Official Full Name
Capsid polyprotein VP90
UniProt Protein Name
Capsid polyprotein VP90
Protein Family
UniProt Gene Name
ORF2
UniProt Entry Name
CAPSD_HASV2

Uniprot Description

The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions. This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry. The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34. This forms contains only 30 spikes located on the icosahedral 2-fold axes. Plays a role in the attachment to target host cell. This attachment induces virion internalization through clathrin-dependent endocytosis ().

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Product Notes

The ASTROVIRUS orf2 (Catalog #AAA214478) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ASTROVIRUS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ASTROVIRUS orf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASTROVIRUS, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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