Rabbit anti-Human Adenosine A2b Receptor (ADORA2b) Polyclonal Antibody | anti-ADORA2b antibody
HRP-Linked Polyclonal Antibody to Adenosine A2b Receptor (ADORA2b)
IHC: 5-20ug/mL
ICC: 5-20ug/mL
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
Observed: 41 kDa
NCBI Description
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Uniprot Description
ADORA2B: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 17p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: adenosine receptor activity, G-protein coupled
Biological Process: relaxation of vascular smooth muscle; activation of MAPK activity; adenylate cyclase activation; positive regulation of interleukin-6 production; positive regulation of mast cell degranulation; positive regulation of guanylate cyclase activity; excretion; G-protein signaling, adenylate cyclase activating pathway; positive regulation of chemokine production; G-protein coupled receptor protein signaling pathway; positive regulation of chronic inflammatory response to non-antigenic stimulus; cellular response to extracellular stimulus; cellular defense response; JNK cascade; adenosine receptor signaling pathway
Research Articles on ADORA2b
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Product Notes
The ADORA2b adora2b (Catalog #AAA2126489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HRP-Linked Polyclonal Antibody to Adenosine A2b Receptor (ADORA2b) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Adenosine A2b Receptor (ADORA2b) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-2ug/mL IHC: 5-20ug/mL ICC: 5-20ug/mL. Researchers should empirically determine the suitability of the ADORA2b adora2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adenosine A2b Receptor (ADORA2b), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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