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Mouse anti-Human Peptidyl Arginine Deiminase Type VI (PADI6) Monoclonal Antibody | anti-PADI6 antibody

Cy3-Linked Monoclonal Antibody to Peptidyl Arginine Deiminase Type VI (PADI6)

Gene Names
PADI6; hPADVI; PREMBL2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G affinity chromatography
Synonyms
Peptidyl Arginine Deiminase Type VI (PADI6); Monoclonal Antibody; Cy3-Linked Monoclonal Antibody to Peptidyl Arginine Deiminase Type VI (PADI6); Peptidyl Arginine Deiminase Type VI; Peptidylarginine deiminase VI; Peptidyl arginine deiminase-like protein; anti-PADI6 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
D3
Specificity
The antibody is a Mouse monoclonal antibody raised against PADI6. It has been selected for its ability to recognize PADI6 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
>=100ug/mL
Please refer to the vial label for the specific concentration. (varies by lot)
Applicable Applications for anti-PADI6 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Cross Reactivity
Human
Immunogen
Recombinant PADI6 (Ser393~Pro694) expressed in E Coli
Conjugation
Cy3
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for anti-PADI6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77,727 Da
NCBI Official Full Name
protein-arginine deiminase type-6
NCBI Official Synonym Full Names
peptidyl arginine deiminase 6
NCBI Official Symbol
PADI6
NCBI Official Synonym Symbols
hPADVI; PREMBL2
NCBI Protein Information
protein-arginine deiminase type-6
UniProt Protein Name
Protein-arginine deiminase type-6
UniProt Gene Name
PADI6
UniProt Synonym Gene Names
PAD6; hPADVI

NCBI Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]

Uniprot Description

PADI6: Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo. Belongs to the protein arginine deiminase family.

Protein type: Cytoskeletal; EC 3.5.3.15; Hydrolase

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: cytoplasm; intermediate filament cytoskeleton; nucleus

Molecular Function: calcium ion binding; protein-arginine deiminase activity

Biological Process: cytoplasm organization and biogenesis; cytoskeleton organization; regulation of translation by machinery localization

Disease: Preimplantation Embryonic Lethality 2

Research Articles on PADI6

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Product Notes

The PADI6 padi6 (Catalog #AAA2125034) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cy3-Linked Monoclonal Antibody to Peptidyl Arginine Deiminase Type VI (PADI6) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Peptidyl Arginine Deiminase Type VI (PADI6) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-2ug/mL IHC: 5-20ug/mL ICC: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PADI6 padi6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peptidyl Arginine Deiminase Type VI (PADI6), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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