17-Beta-Hydroxysteroid Dehydrogenase Type 2 Recombinant Protein | HSD17b2 recombinant protein
Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD17b2)
Gene Names
Hsd17b2; AI194836; AI194967; AI255511
Applications
SDS-Page, Western Blot
Purity
>90%
Synonyms
17-Beta-Hydroxysteroid Dehydrogenase Type 2; Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD17b2); EDH17B2; HSD17; Estradiol 17-Beta-Dehydrogenase 2; Short Chain Dehydrogenase/Reductase Family 9C; Member 2; 20 alpha-hydroxysteroid dehydrogenase; HSD17b2 recombinant protein
Host
E Coli
Purity/Purification
>90%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Gln158~His381
Sequence Length
381
Applicable Applications for HSD17b2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Species
Mouse
Tag
N-terminal His and GST Tag
Subcellular Location
Membrane
Isoelectric Point
9.2
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for HSD17b2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 61.5kDa
Accurate Molecular Mass: 62kDa
Accurate Molecular Mass: 62kDa
NCBI Official Full Name
Estradiol 17-beta-dehydrogenase 2
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 2
NCBI Official Symbol
Hsd17b2
NCBI Official Synonym Symbols
AI194836; AI194967; AI255511
NCBI Protein Information
estradiol 17-beta-dehydrogenase 2
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 2
Protein Family
UniProt Gene Name
Hsd17b2
UniProt Synonym Gene Names
Edh17b2; 17-beta-HSD 2
UniProt Entry Name
DHB2_MOUSE
Uniprot Description
HSD17B2: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein type: EC 1.1.1.62; EC 1.1.1.239; Oxidoreductase; Membrane protein, integral; Lipid Metabolism - androgen and estrogen; Endoplasmic reticulum
Cellular Component: intracellular membrane-bound organelle; membrane; integral to membrane
Molecular Function: estradiol 17-beta-dehydrogenase activity; oxidoreductase activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
Biological Process: response to retinoic acid; metabolic process; in utero embryonic development; lipid metabolic process; androgen biosynthetic process; steroid biosynthetic process; estrogen biosynthetic process; placenta development
Research Articles on HSD17b2
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Product Notes
The HSD17b2 hsd17b2 (Catalog #AAA2123388) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Gln158~His381. AAA Biotech's 17-Beta-Hydroxysteroid Dehydrogenase Type 2 can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the HSD17b2 hsd17b2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "17-Beta-Hydroxysteroid Dehydrogenase Type 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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